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Volume 21, Number 12—December 2015
Dispatch

Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea

Wan Beom Park1, Ranawaka A.P.M. Perera1, Pyoeng Gyun Choe, Eric H.Y. Lau, Seong Jin Choi, June Young Chun, Hong Sang Oh, Kyoung-Ho Song, Ji Hwan Bang, Eu Suk Kim, Hong Bin Kim, Sang Won Park, Nam Joong Kim, Leo Lit Man Poon, Ghazi KayaliComments to Author , and Myoung-don OhComments to Author 
Author affiliations: Seoul National University College of Medicine, Seoul, South Korea (W.B. Park, P.G. Choe, S.J. Choi, J.Y. Chun, H.S. Oh, K.-H. Song, J.H. Bang, E.S. Kim, H.B. Kim, S.W. Park, N.J. Kim, M.-d. Oh); The University of Hong Kong, Pokfulam, Hong Kong, China (R.A.P.M. Perera, E.H.Y. Lau, L.L.M. Poon); Hong Kong University–Pasteur Research Pole, Pokfulam (M. Peiris)

Main Article

Figure

Antibody response kinetics in patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection, by days after illness onset, as determined by using a 50% endpoint plaque reduction neutralization test (PRNT50) (A) and an S1 IgG ELISA (B). Key indicates individual patients; Red indicates patients with severe illness requiring mechanical ventilation; blue indicates patients with severe illness requiring only supplemental oxygen therapy; and green indicates patients with mild illness.

Figure. Antibody response kinetics in patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection, by days after illness onset, as determined by using a 50% endpoint plaque reduction neutralization test (PRNT50) (A) and an S1 IgG ELISA (B). Key indicates individual patients; Red indicates patients with severe illness requiring mechanical ventilation; blue indicates patients with severe illness requiring only supplemental oxygen therapy; and green indicates patients with mild illness. For better presentation, the PRNT50 titers have been jittered vertically (random noise added to prevent overplotting) (7) by adding random numbers to the titers within the range of −0.2 to 0.2 at the log scale. OD, optical density.

Main Article

References
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1These authors contributed equally to this article.

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