Volume 21, Number 12—December 2015
Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea
|Clinical factors||Acceleration factor of time from illness onset to log phase of antibody response
|PRNT50 titer||p value||S1-ELISA OD ratio‡||p value|
|Age >60 y†||0.95||0.73||1.08||0.60|
|Incubation period, d†||0.97||0.06||0.95||<0.001|
|Use of corticosteroid†||1.19||0.33||1.14||0.47|
|Use of antiviral drugs†||1.07||0.61||0.76||0.03|
*Accelerated failure time models were used; acceleration factor >1 means a longer interval to commencement of antibody response. OD, optical density; PRNT50, 50% endpoint plaque reduction neutralization test.
†Effects were adjusted for severity.
‡Increase over S1-ELISA OD >0.8..
1These authors contributed equally to this article.