Volume 21, Number 2—February 2015
CME ACTIVITY - Research
Infectious Causes of Encephalitis and Meningoencephalitis in Thailand, 2003–2005
Table 4
Characteristic | Etiologic classification |
p value | |
---|---|---|---|
Confirmed/probable, n = 54 | Possible/unknown, n = 95 | ||
Male sex, no. (%) | 33 (61) | 51 (54) | 0.38 |
Age, y, median (range) |
9 (0–74) |
17 (0–82) |
0.10 |
Time between onset of neurologic symptoms and admission, d, median (range) | 1 (8–4)† | 1 (12–7)† | 0.35 |
Time between onset of fever and admission, d, median (range) | 4 (31–1)† | 4 (35–2)† | 0.33 |
Temperature, °C, median (range) |
38.0 (36.0–42.0) |
37.7 (35.5–40.2) |
0.03 |
Symptoms during illness, no. (%) | |||
Respiratory | 12 (22) | 27 (28) | 0.41 |
Gastrointestinal | 23 (43) | 36 (38) | 0.57 |
Rash |
4 (7.4) |
14 (15) |
0.30 |
Glasgow Coma Scale score, no. (%) | 0.44 | ||
<8 | 7 (13) | 18 (19) | |
9–12 | 13 (24) | 27 (28) | |
>13 | 34 (63) | 50 (53) | |
Mean (SD) |
12 (3.2) |
12 (3.7) |
0.37 |
Neurologic signs/symptoms, no. (%) | |||
Alteration of consciousness | 35 (65) | 63 (66) | 0.85 |
Lethargy | 27 (50) | 45 (47) | 0.76 |
Seizure | 19 (35) | 48 (50) | 0.07 |
Focal neurologic signs | 19 (35) | 32 (34) | 0.89 |
Personality change | 22 (41) | 39 (41) | 0.97 |
Somnolence | 23 (43) | 34 (36) | 0.44 |
Loss of consciousness | 8 (15) | 28 (30) | 0.04 |
Extreme irritability | 9 (17) | 23 (24) | 0.28 |
Coma | 10 (19) | 15 (16) | 0.67 |
Ataxia | 2 (3.7) | 6 (6.3) | 0.71 |
Headache | 29 (54) | 45 (47) | 0.46 |
Stiff neck |
29 (54) |
29 (31) |
0.01 |
Pentobarbital or paralytic medications for intractable seizures | 15 (28) | 22 (23) | 0.53 |
CSF pleocytosis, no. (%) |
49 (91) |
76 (80) |
0.09 |
Abnormal MRI/CT/cranial U/S findings, no. (%) | 23/31 (74) | 57/69 (83) | 0.33 |
Abnormal EEG, no. (%) |
6/9 (67) |
22/30 (73) |
0.69 |
Length of hospital stay, median days (range) | 13 (1–180) | 16 (1–128) | 0.71 |
Intensive care unit admission, no. (%) | 15 (28) | 33 (35) | 0.38 |
Died, no. (%)‡ | 2 (3.7) | 13 (14) | 0.09 |
*CSF, cerebrospinal fluid; EEG, electroencephalogram, MRI, magnetic resonance imaging; CT, computed tomography; U/S, ultrasonography.
†Ranges indicate no. days before and after hospital admission.
‡All but 1 patient died while hospitalized.
1These authors contributed equally to this article.
2Members are listed at the end of this article.
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