Volume 21, Number 2—February 2015
Outbreak of Henipavirus Infection, Philippines, 2014
||Onset of clinical signs
||Date of sample collection
||IgM ELISA ratio
||NiV SNT titer†
||NiV SNT titer‡
||Nucleic acid detection
||Apr 12||11.8||Neg||1:150||Pos (qPCR) from serum of Apr 12|
||Apr 15||13.2 (6
||1:10||1:200||Pos (NGS) from CSF of Apr 12|
|3 (ILI)||Apr 2||May 21||5||1:40||1:420||NA|
*The cutoff for the IgM NiV ELISA is a ratio of 2, for SNT using infectious NiV is ≥1:4, and for pseudotype-based SNT is 1:80. All samples were serum except for the sample tested by NGS, which was CSF. AES, acute encephalitis syndrome; CSF, cerebrospinal fluid; ILI, influenza-like illness; NA, not applicable; Neg, negative; NGS, next-generation sequencing; NiV, Nipah virus; pos, positive; qPCR, quantitative PCR for NiV; SNT, serum neutralization test.
†Test used infectious NiV.
‡Test used pseudotyped vesicular stomatitis virus.