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Volume 21, Number 3—March 2015
Research

Mycoplasma pneumoniae and Chlamydia spp. Infection in Community-Acquired Pneumonia, Germany, 2011–2012

Roger Dumke, Christiane Schnee, Mathias W. Pletz, Jan Rupp, Enno Jacobs, Konrad Sachse1, Gernot Rohde1Comments to Author , and CAPNETZ Study Group2
Author affiliations: Technical University Dresden Institute of Medical Microbiology and Hygiene, Dresden, Germany (R. Dumke, E. Jacobs); Friedrich-Loeffler-Institut, Jena, Germany (C. Schnee, K. Sachse); Jena University Hospital Center for Infectious Diseases and Infection Control, Jena (M.W. Pletz); CAPNETZ STIFTUNG, Hannover, Germany (M.W. Pletz, J. Rupp, G. Rohde); University of Lübeck, Lübeck, Germany (J. Rupp); Maastricht University Medical Centre, Maastricht, the Netherlands (G. Rohde)

Main Article

Table 3

Demographic and clinical characteristics of patients with community-acquired pneumonia whose respiratory tract samples were tested for Chlamydia spp., Germany, 2011–2012*

Characteristic All, n = 794 Chlamydia-positive, n = 31 Chlamydia-negative, n = 763 p value†
Median age, y (range) 61 (18–102) 64 (18–89) 61 (18–102)
Male sex 56.8 54.8 56.9
BMI (range)
 25.6 (13.9–56.5)
 24.3 (17.7–45.3)
 25.7 (13.9–56.5)
Co-occurring
Chronic pulmonary disease 21.2 32.3 20.7
Chronic renal disease 19.2 0 19.9 p = 0.05
Chronic heart failure 25.7 12.5 26.2
Diabetes mellitus 24.8 25.0 24.8
Cerebro-vascular disease
 9.3
 12.5
 9.2
CURB scores‡
0 56.8 54.8 56.9
1 31.5 41.9 31.0
2 10.5 3.2 10.8
3 1.2 0 1.2
4
 0
 0
 0
Antimicrobial drug pretreatment 29.1 25.8 29.3
Macrolides
 7.9
 0
 8.3
 §
Mortality rate
28 d 1.8 6.5 1.6
180 d 4.7 6.5 4.6

*Values are percentages except as indicated. BMI, body mass index.
†Only significant values are shown. Comparison between Chlamydia-positive and -negative patients by χ2 or Mann-Whitney U test as appropriate.
‡Clinical evaluation of the following risk factors (each scores 1 point): Confusion; blood Urea >7 mmol/L; Respiratory rate ≥30 bpm; Blood pressure <90 (systolic) or ≤60 mm Hg (diastolic).
§Also no significant differences for other antibiotic classes.

Main Article

1Joint senior authors.

2Members of the CAPNETZ Study Group are listed at the end of this article.

Page created: February 18, 2015
Page updated: February 18, 2015
Page reviewed: February 18, 2015
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