Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 21, Number 4—April 2015
Dispatch

Close Relationship of Ruminant Pestiviruses and Classical Swine Fever Virus

Alexander Postel, Stefanie Schmeiser, Tuba Cigdem Oguzoglu, Daniela Indenbirken, Malik Alawi, Nicole Fischer, Adam Grundhoff, and Paul BecherComments to Author 
Author affiliations: University of Veterinary Medicine, Hannover, Germany (A. Postel, S. Schmeiser, P. Becher); Ankara Üniversitesi Veteriner Fakültesi Viroloji Anabilim Dalı Dışkapı, Ankara, Turkey (T.C. Oguzoglu); Heinrich Pette Institute–Leibniz Institute for Experimental Virology, Hamburg, Germany (D. Indenbirken, M. Alawi, A. Grundhoff); University Medical Center Hamburg-Eppendorf, Hamburg (M. Alawi, N. Fischer); German Center for Infection Research Hamburg-Lübeck-Borstel, Hamburg (N. Fischer, A. Grundhoff); German Center for Infection Research Hannover-Braunschweig, Hannover (P. Becher)

Main Article

Figure 1

Phylogenetic and antigenic tree displaying relatedness of pestiviruses Aydin/04 and Burdur/05 to other Pestivirus species. A) For phylogenetic analysis, deduced polyprotein sequences from GenBank were used (CSFV: J04358, GU233734, JX218094, AY568569, GQ902941, KJ619377, AY382481, AF326963, X87939, AF099102, AY578687, AY646427; BDV: AF037405, U70263, KC963426, AF144618, GQ902940, KF918753, GU270877; BVDV-1: EF101530, AF220247, M96751, AF091605; BVDV-2: AB567658, GQ888686, AF502399, U18059; HoBi-l

Figure 1. Phylogenetic and antigenic tree displaying relatedness of pestiviruses Aydin/04 and Burdur/05 to other Pestivirus species. A) For phylogenetic analysis, deduced polyprotein sequences from GenBank were used (CSFV: J04358, GU233734, JX218094, AY568569, GQ902941, KJ619377, AY382481, AF326963, X87939, AF099102, AY578687, AY646427; BDV: AF037405, U70263, KC963426, AF144618, GQ902940, KF918753, GU270877; BVDV-1: EF101530, AF220247, M96751, AF091605; BVDV-2: AB567658, GQ888686, AF502399, U18059; HoBi-like: AB871953, NC012812; giraffe-like: NC003678, KJ660072; Pronghorn and Bungowannah: NC024018, NC023176). Bootstrap values were calculated for 1,000 iterations. Only significant bootstrap values (≥700) of major nodes are given in the tree. Trees were displayed by using Dendroscope (10). Scale bar indicates base substitutions per site. B) Antigenic tree based on coefficients of antigenic similarity (R values) displaying antigenic relatedness of pestiviruses Aydin/04 and Burdur/05 to representative CSFV and BDV strains. R values <25 indicate significant antigenic differences as representing >4-fold differences in titers. R values >25 are considered not significant and are therefore not drawn to scale. Boldface indicates pestiviruses circulating among sheep and goat herds in Turkey. BDV, border disease virus; BVDV, bovine viral diarrhea virus; CSFV, classical swine fever virus; G, genotype.

Main Article

References
  1. Simmonds  P, Becher  P, Collett  MS, Gould  EA, Heinz  FX, Meyers  G, Family Flaviviridae. In: Virus taxonomy. Ninth report of the International Committee on Taxonomy of Viruses. San Diego: Elsevier; 2012. p. 1003–20.
  2. Edwards  S, Fukusho  A, Lefevre  PC, Lipowski  A, Pejsak  Z, Roehe  P, Classical swine fever: the global situation. Vet Microbiol. 2000;73:103–19. DOIPubMedGoogle Scholar
  3. Moennig  V, Floegel-Niesmann  G, Greiser-Wilke  I. Clinical signs and epidemiology of classical swine fever: a review of new knowledge. Vet J. 2003;165:11–20. DOIPubMedGoogle Scholar
  4. Postel  A, Moennig  V, Becher  P. Classical swine fever in Europe—the current situation. Berl Munch Tierarztl Wochenschr. 2013;126:468–75 .PubMedGoogle Scholar
  5. Kawanishi  N, Tsuduku  S, Shimizu  H, Ohtani  Y, Kameyama  K, Yamakawa  M, First isolation of border disease virus in Japan is from a pig farm with no ruminants. Vet Microbiol. 2014;171:210–4. DOIPubMedGoogle Scholar
  6. Oguzoglu  TC, Tan  MT, Toplu  N, Demir  AB, Bilge-Dagalp  S, Karaoglu  T, Border disease virus (BDV) infections of small ruminants in Turkey: a new BDV subgroup? Vet Microbiol. 2009;135:374–9. DOIPubMedGoogle Scholar
  7. EU diagnostic manual for classical swine fever (CSF) diagnosis: technical part. 2007 [cited 2014 Jan 6]. http://www.tiho-hannover.de/fileadmin/user_upload/tiho_hannover/kliniken_institute/21_virologie/eurl/Technical_Annex_Draft_2007.pdf
  8. Becher  P, Schmeiser  S, Oguzoglu  TC, Postel  A. Complete genome sequence of a novel pestivirus from sheep. J Virol. 2012;86:11412. DOIPubMedGoogle Scholar
  9. Fischer  N, Rohde  H, Indenbirken  D, Gunther  T, Reumann  K, Lutgehetmann  M, Rapid metagenomic diagnostics for suspected outbreak of severe pneumonia. Emerg Infect Dis. 2014;20:1072–5. DOIPubMedGoogle Scholar
  10. Huson  DH, Scornavacca  C. Dendroscope 3: an interactive tool for rooted phylogenetic trees and networks. Syst Biol. 2012;61:1061–7. DOIPubMedGoogle Scholar
  11. Postel  A, Schmeiser  S, Bernau  J, Meindl-Boehmer  A, Pridotkas  G, Dirbakova  Z, Improved strategy for phylogenetic analysis of classical swine fever virus based on full-length E2 encoding sequences. Vet Res. 2012;43:50. DOIPubMedGoogle Scholar
  12. Simmonds  P. SSE: a nucleotide and amino acid sequence analysis platform. BMC Res Notes. 2012;5:50. DOIPubMedGoogle Scholar
  13. Becher  P, Avalos Ramirez  R, Orlich  M, Cedillo Rosales  S, Konig  M, Schweizer  M, Genetic and antigenic characterization of novel pestivirus genotypes: implications for classification. Virology. 2003;311:96–104. DOIPubMedGoogle Scholar
  14. Thabti  F, Letellier  C, Hammami  S, Pepin  M, Ribiere  M, Mesplede  A, Detection of a novel border disease virus subgroup in Tunisian sheep. Arch Virol. 2005;150:215–29 . DOIPubMedGoogle Scholar

Main Article

Page created: March 17, 2015
Page updated: March 17, 2015
Page reviewed: March 17, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external