Volume 21, Number 5—May 2015
CME ACTIVITY - Perspective
Recent US Case of Variant Creutzfeldt-Jakob Disease—Global Implications
Figure 2
![Magnetic resonance imaging (MRI) results for a US patient with variant Creutzfeldt-Jakob disease. A) T1 sequence. B) T2 FLAIR sequence showing the “pulvinar” or “hockey stick” sign (arrowhead). Initial Diffusion Weighted Imaging (DWI) (C) and Apparent Diffusion Coefficient (ADC) (D) images show subtle restricted diffusion in right primary motor cortex; subsequent MRIs show increasing hyperintensity on DWI (E,G) and further attenuation on ADC (F,H), consistent with the “cortical ribbon” sign. Ori](/eid/images/14-2017-F2.jpg)
Figure 2. Magnetic resonance imaging (MRI) results for a US patient with variant Creutzfeldt-Jakob disease. T1 sequence (A) and T2 FLAIR sequence (B) show the “pulvinar” or “hockey stick” sign (arrowhead). Initial diffusion weighted imaging (DWI) (C) and apparent diffusion coefficient (ADC) (D) images show subtle restricted diffusion in the right primary motor cortex (arrows). Subsequent MRIs show increasing hyperintensity (arrows) on DWI (E, then G) and further attenuation (arrows) on ADC (F, then H), consistent with the “cortical ribbon” sign.
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