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Volume 21, Number 6—June 2015

Drug Resistance–Associated Mutations in Mycoplasma genitalium in Female Sex Workers, Japan

Takashi DeguchiComments to Author , Mitsuru Yasuda, Kengo Horie, Kensaku Seike, Mina Kikuchi, Kohsuke Mizutani, Tomohiro Tsuchiya, Shigeaki Yokoi, Masahiro Nakano, and Shinji Hoshina
Author affiliations: Gifu University, Gifu, Japan (T. Deguchi, M. Yasuda, K. Horie, K. Seike, M. Kikuchi, K. Mizutani, T. Tsuchiya, S. Yokoi, M. Nakano); Hoshina Clinic, Kyoto, Japan (S. Hoshina)

Main Article

Table 2

Mutations in the 23S rRNA gene and amino acid changes in GyrA and ParC in Mycoplasma genitalium detected in female sex workers, Japan*

Female sex worker Specimen type Mutations in the 23S rRNA gene Amino acid changes in
GyrA ParC
1 Vaginal swab A-2058→G
2 Vaginal swab NA
3 Vaginal swab
4 Vaginal swab
5 Vaginal swab A-2058→G
6 Vaginal swab A-2059→G Ser-80→Ile
7 Vaginal swab NA NA
8 Vaginal swab
9 Vaginal swab
10 Vaginal swab
11 Throat washing NA NA NA
12 Vaginal swab
13 Vaginal swab NA
14 Vaginal swab A-2059→G Ser-80→Ile
15 Vaginal swab A-2058→G Ser-80→Asn
16 Vaginal swab NA Ser-80→Ile
17 Vaginal swab Ser-80→Ile
18 Vaginal swab
19 Vaginal swab Ser-80→Asn
20 Vaginal swab A-2058→G Ser-80→Asn
21 Vaginal swab A-2058→G
22 Vaginal swab A-2058→G NA

*The nucleotide positions in the 23S rRNA gene and the amino acid positions in ParC are numbered according to Escherichia coli numbering. –, no mutations in the 23S rRNA gene nor amino acid changes in GyrA or ParC were found in the analyzed regions; NA, specimens could not be analyzed for the 23S rRNA, gyrA, or parC genes.

Main Article

Page created: May 15, 2015
Page updated: May 15, 2015
Page reviewed: May 15, 2015
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