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Volume 21, Number 7—July 2015
CME ACTIVITY - Research

Parechovirus Genotype 3 Outbreak among Infants, New South Wales, Australia, 2013–2014

Germaine Cumming1Comments to Author , Ameneh Khatami, Brendan J. McMullan, Jennie Musto, Kit Leung, Oanh Nguyen, Mark J. Ferson, Georgina Papadakis, and Vicky Sheppeard
Author affiliations: Health Protection New South Wales, Sydney, New South Wales, Australia (G. Cumming, J. Musto, V. Sheppeard); New South Wales Ministry of Health, Sydney (G. Cumming, K. Leung); The Children’s Hospital at Westmead, Sydney (A. Khatami); Sydney Children’s Hospital, Sydney (B.J. McMullan); University of New South Wales, Sydney (B.J. McMullan, M.J. Ferson); Western Sydney Local Health District, Sydney (O. Nguyen); South Eastern Sydney Local Health District, Sydney (M.J. Ferson); Victorian Infectious Disease Reference Laboratory, Melbourne, Victoria, Australia (G. Papadakis)

Main Article

Table 2

HPeV testing of specimens from patients from New South Wales, received at the VIDRL, Melbourne, Victoria, Australia, November 1, 2013–February 28, 2014, by specimen type*

Sample and result
 Specimens, no. (%)
 Patients, no. (%)
Total 420 (100) 308 (100)
CSF
Total samples tested 168 (40) 161 (52)
HPeV+ (mean Ct 31.6)† 123 (73) 116 (72)
PCR+ for HPeV and EV 1 (1) 1 (1)
Stool
Total samples tested 156 (37) 147 (48)
HPeV+ (mean Ct 27.2) 114 (73) 106 (72)
PCR+ for HPeV and EV 2 (1) 2 (1)
Other
Total samples tested 96 (23) 8 (28)
HPeV+ 52 (54) 45 (52)
PCR+ for HPeV and EV 1 (1) 1 (1)
Sequenced: HPeV3 41 (14) 41 (21)

*CSF, cerebrospinal fluid; Ct, cycle threshold; EV, enterovirus; HPeV, human parechovirus; VIDRL, Victorian Infectious Disease Reference Laboratory: +, positive.
†At VIDRL, PCRs are run for 45 cycles, so any Ct value greater than 45 is considered negative.

Main Article

1Current affiliation: Independent consultant, Freshwater, New South Wales, Australia

Page created: June 15, 2015
Page updated: June 15, 2015
Page reviewed: June 15, 2015
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