Volume 21, Number 7—July 2015
Dispatch
Evaluation of Patients under Investigation for MERS-CoV Infection, United States, January 2013–October 2014
Table 1
Characteristics of 490 PUIs for MERS-CoV, United States, January 1, 2013–October 31, 2014*
Characteristic | Value |
---|---|
Sex, M/F | 296 (60.4)/186 (38.0) |
Median age, y (range) |
48 (0.3–89) |
Symptom | |
Cough | 393(80.2) |
Fever | 388 (79.2) |
Shortness of breath | 220 (44.9) |
Chills† | 153 (35.1) |
Myalgia† | 140 (32.1) |
Sore throat | 134 (27.4) |
Headache† | 106 (24.3) |
Diarrhea† | 58 (13.3) |
Abdominal pain† |
34 (7.8) |
Hospitalized | 292 (59.6) |
Intensive care unit | 112 (38.4) |
Mechanical ventilation |
61 (20.9) |
Clinical finding | |
Pneumonia‡ | 236 (48.2) |
Acute respiratory distress syndrome‡ | 48 (9.8) |
Renal failure |
22 (4.5) |
Died |
11 (2.2) |
Underlying condition† | |
Immunosuppression | 55 (12.6) |
Diabetes | 40 (9.2) |
Hypertension | 27 (6.2) |
Cardiac disease | 23 (5.3) |
Asthma | 20 (4.6) |
Chronic pulmonary disease | 11 (2.5) |
Hyperlipidemia | 9 (2.1) |
Pregnant | 8 (1.8) |
Renal disease | 7 (1.6) |
Other |
12 (2.8) |
Specific job classification† | |
Health care worker | 35 (8.0) |
US military |
9 (2.1) |
MERS-CoV rRT-PCR testing | |
Specimen type | |
Upper respiratory | 414 (84.5) |
Lower respiratory | 242 (49.4) |
Serum | 235 (48) |
Stool | 40 (8.2) |
MERS-CoV positive |
2 (0.4) |
Serologic testing for MERS-CoV | |
Tested | 67 (13.7) |
MERS-CoV positive |
2 (0.4) |
Other pathogens detected§ | |
Influenza A virus | 41 (8.4) |
Rhinovirus/enterovirus | 37 (7.6) |
Influenza B virus | 13 (2.7) |
Streptococcus pneumoniae | 11 (2.2) |
Human metapneumovirus | 6 (1.2) |
Adenovirus | 5 (1.0) |
Coronavirus | 4 (0.8) |
Respiratory syncytial virus | 4 (0.8) |
Parainfluenzavirus | 3 (0.6) |
Chlamydophila pneumoniae | 2 (0.4) |
Legionella pneumoniae | 2 (0.4) |
Other | 16 (3.3) |
*Data are no. (%) unless otherwise specified. MERS-CoV, Middle East respiratory syndrome coronavirus; PUI, patient under investigation; rRT-PCR, real-time reverse transcription PCR.
†Included only in 2 most recent versions of PUI short form (N = 436).
‡Forty-one PUIs had pneumonia and acute respiratory distress syndrome.
§Etiologic pathogen not reported for 359 (73%) PUIs; >1 pathogen identified for some PUIs.