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Volume 21, Number 7—July 2015
Research

Malaria Prevalence among Young Infants in Different Transmission Settings, Africa

Serign J. Ceesay, Lamine Koivogui, Alain Nahum, Makie Abdoulie Taal, Joseph Okebe, Muna Affara, Lama Eugène Kaman, Francis Bohissou, Carine Agbowai, Benoit Gniouma Tolno, Alfred Amambua-Ngwa, NFaly Bangoura, Daniel Ahounou, Abdul Khalie Muhammad, Stephan Duparc, Kamal Hamed, David Ubben, Kalifa Bojang, Jane Achan, and Umberto D’AlessandroComments to Author 
Author affiliations: Medical Research Council Unit, Fajara, The Gambia (S.J. Ceesay, J. Okebe, M. Affara, A. Amambua-Ngwa, A.K. Muhammad, K. Bojang, J. Achan, U. D’Alessandro); Institut National de Santé Publique, Conakry, Guinea (L. Koivogui, L.E. Kaman, B.G. Tolno); Centre de Recherches Entomologiques de Cotonou, Cotonou, Benin (A. Nahum, F. Bohissou, C. Agbowai, D. Ahounou); National Public Health Laboratory, Kotu, The Gambia (M.A. Taal); Préfectoral de la santé de Faranah, Guinea (N. Bangoura); Medicines for Malaria Venture, Geneva, Switzerland (S. Duparc, D. Ubben); Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA (K. Hamed); London School of Hygiene and Tropical Medicine, London, UK (U. D’Alessandro); Institute of Tropical Medicine, Antwerp, Belgium (U. D’Alessandro)

Main Article

Table 4

Characteristics of 0- to 6-month-old infants with malaria in 3 African countries with different transmission settings

Variable No malaria, n (%), N = 2,036 Malaria, n (%), N = 183 Odds ratio (95% CI)
 p value
Crude Adjusted*
Country
The Gambia 709 (96.6) 25 (3.4) Reference Reference
Benin 736 (96.7) 25 (3.3) 0.96 (0.55–1.69) 0.74 (0.41–1.32) 0.307
Guinea
 591 (81.6)
 133 (18.4)
 6.38 (4.11–9.92)
 5.28 (3.30–8.44)
 0.001
Sex
F 1,040 (92.8) 81 (7.2)
M
 996 (90.7)
 102 (9.3)
 1.31 (0.97-1.78)
 1.13 (0.80–1.59)
 0.491
Fever or history of fever†
No 1,573 (94.4) 94 (5.6)
Yes
 458 (83.7)
 89 (16.3)
 3.25 (2.38–4.44)
 1.65 (1.15–2.37)
 0.007
Anemia‡
No 1,724 (95.5) 81 (4.5)
Yes
 312 (75.4)
 102 (24.6)
 6.96 (5.01–9.67)
 5.54 (3.91–7.84)
 0.001
Weight, kg
<5 1,225 (88.7) 156 (11.3)
>5 811 (96.8) 27 (3.2) 0.26 (0.17–0.40) 0.29 (0.19–0.45) 0.001

*Adjusted for country, sex, fever, anemia, age, and weight.
†History of fever refers to fever in the 24 h before the structured questionnaire was completed.
‡Defined as hemoglobin level of <10 g/dL.

Main Article

Page created: June 12, 2015
Page updated: June 12, 2015
Page reviewed: June 12, 2015
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