Volume 21, Number 8—August 2015
Differentiation of Acute Q Fever from Other Infections in Patients Presenting to Hospitals, the Netherlands1
|Characteristic||Study group||Control group||p value|
|Hospitalized||57/82 (70)||49/52 (94)||0.001†|
|Need for ICU||2/57 (4)||9/49 (18)||0.002†|
|Need for respiratory support||1/57 (2)||8/49 (16)||0.001†|
|Mean ± SD duration of hospitalization, d||9 ± 7||17 ± 15||0.001‡|
|Mean ± SD duration of time in ICU, d||5 ± 1||14 ± 10||0.266‡|
|Development of chronic Q fever||6/59 (10)||NA||NA|
|Development of long-lasting fatigue§||6/56 (11)||NA||NA|
|Death||5/82 (6)||10/52 (19)||0.019†|
|Q fever–related death||1/82 (1)¶||NA||NA|
|Indication for prophylaxis||16/82 (20)||NA||NA|
|Development of chronic Q fever|
|Prophylactic treatment||0/8 (0)||NA||NA|
|No prophylactic treatment||3/6 (50)||NA||0.018#|
*Values are no. positive/no. tested (%) unless otherwise indicated. ICU, intensive care unit; NA, not applicable.
†By χ2 test.
‡By Student t-test.
§Defined as persisting fatigue for >6 mo after acute Q fever in the absence of chronic Q fever.
¶This patient died of consequences of an infected vascular prosthesis caused by chronic Q fever.
#By unilateral Barnard exact test.
1Preliminary results from this study were presented as a poster (P1851) at the 22th annual European Congress of Clinical Microbiology and Infectious Diseases, March 31–April 3, 2012, London, UK.