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Volume 21, Number 8—August 2015
Research

Differentiation of Acute Q Fever from Other Infections in Patients Presenting to Hospitals, the Netherlands1

Stephan P. KeijmelComments to Author , Elmer Krijger, Corine E. Delsing, Tom Sprong, Marrigje H. Nabuurs-Franssen, and Chantal P. Bleeker-Rovers
Author affiliations: Radboud university medical center, Nijmegen, the Netherlands (S.P. Keijmel, E. Krijger, C.P. Bleeker-Rovers); Medical Spectrum Twente, Enschede, the Netherlands (C.E. Delsing); Canisius Wilhelmina Hospital, Nijmegen (T. Sprong, M.H. Nabuurs-Franssen)

Main Article

Table 4

Laboratory values for patients with acute Q fever and control group with negative serologic results for Q fever, the Netherlands*

Laboratory value Day† Study group, n = 82
 Control group, n = 52
 p value‡
Mean No. tested Mean No. tested
Hemoglobin, mmol/L; reference range: men 8.1–10.7 mmol/L, women 7.3–9.7 mmol/L 0 8.3 77 8.0 51 NS
1 7.4 28 7.3 34 NS
2–3 7.7 27 7.0 29 0.036
4–6 7.6 27 7.0 29 NS
Leukocytes, × 109 cells/L; reference range 3.5–11.0 × 109 cells/L 0 9.0 80 11.5 50 0.006
1 8.5 40 10.8 28 0.043
2–3 8.0 34 11.1 33 0.021
4–6 10.9 28 9.2 31 NS
Platelets, × 109/L; reference range 20–350 × 109/L 0 239 78 208 50 NS
1 242 23 178 29 0.038
2–3 229 19 172 26 0.042
4–6 298 24 208 27 0.011
Total bilirubin, μmol/L; reference value <17 μmol/L 0 14 26 16 20 NS
1 12 14 14 8 NS
2–3 9 12 28 6 0.017
4–6 8 12 9 6 NS
AP, U/L; reference value <120 U/L 0 104 75 85 50 NS
1 127 19 75 12 0.047
2–3 126 26 66 12 0.010
4–6 145 23 95 15 0.036
ALT, U/L; reference value <45 U/L 0 45 76 37 49 NS
1 64 22 58 16 NS
2–3 66 30 40 13 0.050
4–6 81 22 84 18 NS
γ-GT, U/L; reference value: men <50 U/L, women <35 U/L 0 74 68 65 49 NS
1 117 21 53 12 0.030
2–3 106 27 42 9 0.007
4–6 112 22 66 14 0.050
CRP, mg/L; reference value <10 mg/L 0 167 79 117 50 0.015
1 184 44 150 37 NS
2–3 132 46 147 32 NS
4–6 76 41 98 27 NS
Urea, mmol/L; reference value 2.5–7 mmol/L 0 6.4 79 8.6 51 0.039
1 6.4 33 7.9 35 NS
2–3 5.4 38 8.7 35 0.014
4–6 5.8 34 9.3 30 0.018
Creatinine, μmol/L; reference value: men <110 μmol/L, women <90 μmol/L 0 86 80 105 52 0.042
1 84 38 103 38 NS
2–3 79 37 103 37 NS
4–6 81 36 136 31 NS

*NS, not significant; AP, alkaline phosphatase; ALT, alanine aminotransferase; γ-GT, γ-glutamyl transpeptidase; CRP, C-reactive protein.
†Day 0 is the day of coming to the hospital.
‡By Student t-test.

Main Article

1Preliminary results from this study were presented as a poster (P1851) at the 22th annual European Congress of Clinical Microbiology and Infectious Diseases, March 31–April 3, 2012, London, UK.

Page created: July 14, 2015
Page updated: July 14, 2015
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