Volume 21, Number 8—August 2015
Research
Differentiation of Acute Q Fever from Other Infections in Patients Presenting to Hospitals, the Netherlands1
Table 4
Laboratory values for patients with acute Q fever and control group with negative serologic results for Q fever, the Netherlands*
Laboratory value | Day† | Study group, n = 82 |
Control group, n = 52 |
p value‡ | ||
---|---|---|---|---|---|---|
Mean | No. tested | Mean | No. tested | |||
Hemoglobin, mmol/L; reference range: men 8.1–10.7 mmol/L, women 7.3–9.7 mmol/L | 0 | 8.3 | 77 | 8.0 | 51 | NS |
1 | 7.4 | 28 | 7.3 | 34 | NS | |
2–3 | 7.7 | 27 | 7.0 | 29 | 0.036 | |
4–6 | 7.6 | 27 | 7.0 | 29 | NS | |
Leukocytes, × 109 cells/L; reference range 3.5–11.0 × 109 cells/L | 0 | 9.0 | 80 | 11.5 | 50 | 0.006 |
1 | 8.5 | 40 | 10.8 | 28 | 0.043 | |
2–3 | 8.0 | 34 | 11.1 | 33 | 0.021 | |
4–6 | 10.9 | 28 | 9.2 | 31 | NS | |
Platelets, × 109/L; reference range 20–350 × 109/L | 0 | 239 | 78 | 208 | 50 | NS |
1 | 242 | 23 | 178 | 29 | 0.038 | |
2–3 | 229 | 19 | 172 | 26 | 0.042 | |
4–6 | 298 | 24 | 208 | 27 | 0.011 | |
Total bilirubin, μmol/L; reference value <17 μmol/L | 0 | 14 | 26 | 16 | 20 | NS |
1 | 12 | 14 | 14 | 8 | NS | |
2–3 | 9 | 12 | 28 | 6 | 0.017 | |
4–6 | 8 | 12 | 9 | 6 | NS | |
AP, U/L; reference value <120 U/L | 0 | 104 | 75 | 85 | 50 | NS |
1 | 127 | 19 | 75 | 12 | 0.047 | |
2–3 | 126 | 26 | 66 | 12 | 0.010 | |
4–6 | 145 | 23 | 95 | 15 | 0.036 | |
ALT, U/L; reference value <45 U/L | 0 | 45 | 76 | 37 | 49 | NS |
1 | 64 | 22 | 58 | 16 | NS | |
2–3 | 66 | 30 | 40 | 13 | 0.050 | |
4–6 | 81 | 22 | 84 | 18 | NS | |
γ-GT, U/L; reference value: men <50 U/L, women <35 U/L | 0 | 74 | 68 | 65 | 49 | NS |
1 | 117 | 21 | 53 | 12 | 0.030 | |
2–3 | 106 | 27 | 42 | 9 | 0.007 | |
4–6 | 112 | 22 | 66 | 14 | 0.050 | |
CRP, mg/L; reference value <10 mg/L | 0 | 167 | 79 | 117 | 50 | 0.015 |
1 | 184 | 44 | 150 | 37 | NS | |
2–3 | 132 | 46 | 147 | 32 | NS | |
4–6 | 76 | 41 | 98 | 27 | NS | |
Urea, mmol/L; reference value 2.5–7 mmol/L | 0 | 6.4 | 79 | 8.6 | 51 | 0.039 |
1 | 6.4 | 33 | 7.9 | 35 | NS | |
2–3 | 5.4 | 38 | 8.7 | 35 | 0.014 | |
4–6 | 5.8 | 34 | 9.3 | 30 | 0.018 | |
Creatinine, μmol/L; reference value: men <110 μmol/L, women <90 μmol/L | 0 | 86 | 80 | 105 | 52 | 0.042 |
1 | 84 | 38 | 103 | 38 | NS | |
2–3 | 79 | 37 | 103 | 37 | NS | |
4–6 | 81 | 36 | 136 | 31 | NS |
*NS, not significant; AP, alkaline phosphatase; ALT, alanine aminotransferase; γ-GT, γ-glutamyl transpeptidase; CRP, C-reactive protein.
†Day 0 is the day of coming to the hospital.
‡By Student t-test.
1Preliminary results from this study were presented as a poster (P1851) at the 22th annual European Congress of Clinical Microbiology and Infectious Diseases, March 31–April 3, 2012, London, UK.