Volume 21, Number 8—August 2015
Dispatch
Risk Factors for Serogroup C Meningococcal Disease during Outbreak among Men who Have Sex with Men, New York City, New York, USA
, Sharon K. Greene, Byron F. Robinson, Don Weiss, and the Meningococcal Investigation Team
Table 2
Risk factors for meningococcal disease among case-patients with outbreak-related serogroup C meningococcal disease and controls with amebiasis or giardiasis, New York City, New York, USA, 2012–2013*
| Variable | Case-patients, no. responded/total (%), n = 17 | Controls, no. responded/total (%), n = 51 | Crude matched odds ratio (95% CI) | Matched odds ratio adjusted for HIV infection (95% CI) |
|---|---|---|---|---|
| Black race | 10/17 (58.8) | 5/50 (10.0) | 12.0 (2.8–81.6) | 8.0 (1.6–63.7) |
| Household with >1 other person | 9/16 (56.3) | 10/51 (19.6) | 5.6 (1.5–27.0) | 3.7 (1.0–18.0) |
| Tobacco smoking | 6/17 (35.3) | 14/50 (28.0) | 1.4 (0.4–4.5) | 0.9 (0.2–3.3) |
| Shared a drink | 5/11 (45.5) | 14/39 (35.9) | 1.1 (0.2–4.8) | 1.2 (0.3–5.5) |
| Drug use in month before illness onset | ||||
| Marijuana | 3/15 (20.0) | 13/51 (25.5) | 0.7 (0.1–2.9) | 0.5 (0.1–2.4) |
| Methamphetamine | 7/17 (41.2)† | 0/50 (0) | 28.8 (5.6–∞)‡ | 16.6 (3.1–∞)‡ |
| Cocaine | 4/14 (28.6) | 0/51 (0) | 15.9 (2.7–∞)‡ | 11.2 (1.8–∞)‡ |
| Sexual risk | ||||
| Sex with >1 man during month before illness onset | 8/13 (61.5) | 18/51 (35.3) | 2.6 (0.7–10.7) | 2.8 (0.7–13.7) |
| Met a male sex partner during month before illness onset online or at bar or party versus other ways§ | 7/10 (70.0) | 21/40 (52.5) | 2.1 (0.5–11.6) | 1.8 (0.4–10.6) |
| Chlamydia, gonorrhea, or syphilis diagnoses during the year before diagnosis date¶ | 9/17 (52.9) | 6/51 (11.8) | 7.2 (2.0–33.8) | 4.7 (1.2–23.5) |
| HIV infected | 10/17 (58.8) | 13/51 (25.5) | 6.4 (1.5–45.1) | NA |
*Denominators exclude unknown and refused answers. Values in bold indicate mid-p exact p<0.05. NA, not applicable.
†One patient answered don't know, but laboratory testing at hospital indicated methamphetamine use.
‡Median unbiased estimate of the odds ratio.
§Other ways of meeting included work, school, through a friend, gym, sports group, sex party, or other.
¶Diagnosis date refers to the diagnosis date of serogroup C meningococcal disease for case-patients and diagnosis date of amebiasis or giardiasis for controls.
1Members of this team are listed at the end of this article.