Volume 21, Number 8—August 2015
Dispatch
Infections with Candidatus Neoehrlichia mikurensis and Cytokine Responses in 2 Persons Bitten by Ticks, Sweden
Table 2
Evolution of Candidatus Neoehrlichia mikurensis gene copy numbers and antibody levels to Borrelia burgdorferi sensu lato complex and Anaplasma phagocytophilum for patient 2, Sweden
Characteristic | Days after inclusion in study |
||
---|---|---|---|
0 | 65 | 98 | |
Clinical manifestations |
None |
Rash on left breast |
None |
Candidatus N. mikurensis DNA in plasma, gene copies/mL | 0 | 260 | 1300 |
Serum B. burgdorferi sensu lato IgM (points)* | Negative (0) | Negative (2) | Negative (1) |
B. burgdorferi sensu lato antigens |
|||
Positive reactivity |
None |
None |
None |
Borderline reactivity | None | p39 | p39 |
Serum B. burgdorferi sensu lato IgG (points)† | Negative (0) | Negative (4) | Negative (4) |
B. burgdorferi sensu lato antigens |
|||
Positive reactivity |
None |
VlsE |
VlsE |
Borderline reactivity | None | None | None |
Serum A. phagocytophilum IgG (1:64)‡ | ± | + | ++ |
*Reactivity to either outer surface protein C alone or to 2 antigens was required for a positive IgM response.
†Reactivity to >2 antigens was required for a positive IgG response.
‡Every serum sample was tested at a dilution of 1/64. ±, weakly positive; +, positive; ++, strongly positive.
1These authors contributed equally to this article.