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Volume 21, Number 9—September 2015
Emerging Infections Program

Encephalitis Surveillance through the Emerging Infections Program, 1997–2010

Karen C. BlochComments to Author  and Carol A. Glaser
Author affiliations: Vanderbilt University, Nashville, Tennessee, USA (K.C. Bloch); Kaiser Permanente, Oakland, California, USA (C.A. Glaser)

Main Article

Table 2

Core diagnostic testing algorithm for the Emerging Infections Program Encephalitis Project, 1997–2010*

Pathogen Specimen type Test type Seasonality
Adenovirus NP swab PCR Year-round
Arbovirus panel† Serum Serology May–October
Enteroviruses CSF PCR Year-round
NP swab PCR Year-round
Rectal swab PCR Year-round
Epstein-Barr virus CSF PCR Year-round
Serum Serology Year-round
Herpes simplex virus 1 and 2 CSF PCR Year-round
Human herpesvirus 6 CSF PCR Year-round
Influenza virus A and B NP swab PCR November–April
Parainfluenza virus 1–3 NP swab PCR November–April
Rotavirus Rectal swab Antigen November–April
Varicella zoster virus CSF PCR Year-round
West Nile virus CSF Serology May–October

Bartonella spp. Serum Serology Year-round
Chlamydia pneumoniae NP swab PCR Year-round
Ehrlichia spp. Whole blood PCR May–October
Serum Serology May–October
Mycoplasma pneumoniae NP swab PCR Year-round
Serum Serology Year-round
Rickettsia spp. Serum Serology May–October
Treponema pallidum CSF VDRL Year-round
Serum RPR Year-round

*Diagnostic testing algorithm at the Tennessee site; regional differences and testing availability associated with minor variations in core testing at the California site. Additional supplementary testing was performed when indicated based on individualized epidemiologic, demographic, clinical, or radiographic features. CSF, cerebrospinal fluid; NP, nasopharyngeal; VDRL, venereal disease research laboratory test; RPR, rapid plasma reagin.
†Arbovirus panel included Lacrosse virus, St. Louis encephalitis virus, Western equine encephalitis virus, and Eastern equine encephalitis virus.

Main Article

Page created: August 14, 2015
Page updated: August 14, 2015
Page reviewed: August 14, 2015
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