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Volume 22, Number 1—January 2016
Research

Waterborne Elizabethkingia meningoseptica in Adult Critical Care1

Luke S.P. MooreComments to Author , Daniel S. Owens, Annette Jepson, Jane F. Turton, Simon Ashworth, Hugo Donaldson, and Alison H. Holmes
Author affiliations: Imperial College Healthcare NHS Trust, London, UK (L.S.P. Moore, A. Jepson, S. Ashworth, H. Donaldson, A.H. Holmes); Imperial College London, London. (L.S.P. Moore, A.H. Holmes); St. George’s Healthcare NHS Trust, London (D.S. Owens); Public Health England, London (J.F. Turton)

Main Article

Table 2

MICs of selected antimicrobial agents tested against a representative isolate from an Elizabethkingia meningoseptica outbreak strain from an adult critical care unit, West London, UK, 2012–2013*

Antimicrobial agent MIC, mg/L Interpretation
Ceftazidime 256 Nonsusceptible
Piperacillin/tazobactam 16 Susceptible
Meropenem >32 Nonsusceptible
Imipenem 64 Nonsusceptible
Aztreonam >64 Nonsusceptible
Gentamicin 16 Nonsusceptible
Tobramycin >32 Nonsusceptible
Amikacin 32 Nonsusceptible
Colistin >32 Nonsusceptible
Ciprofloxacin 1 Intermediate
Minocycline 0.5 Unknown
Trimethoprim/sulfamethoxazole 0.25 Susceptible

*MICs were determined by serial agar dilution by using established methods (24). Interpretation of MICs used established British Society of Chemotherapy breakpoints. The intrinsic metallo- and extended-spectrum-β-lactamases exhibited by E. meningoseptica mean the apparent in vitro susceptibility of the organism to piperacillin/tazobactam should be viewed with caution.

Main Article

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Main Article

1Preliminary findings of this study were presented, in part, at the 27th European Society for Intensive Care Medicine conference, Barcelona, Spain, September 27– October 1, 2014.

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Page updated: December 18, 2015
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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