Volume 22, Number 1—January 2016
Dispatch
Hemagglutinin Gene Clade 3C.2a Influenza A(H3N2) Viruses, Alachua County, Florida, USA, 2014–15
John Lednicky, Nicole M. Iovine, Joe Brew, Julia Loeb, Jonathan D. Sugimoto, Kenneth H. Rand, and J. Glenn Morris
Table 1
Amino acid sequences at hemagglutinin major immunogenic epitopes A and B1 of influenza A(H3N2) viruses, Gainesville, Florida, USA, November 2014
| Strain | Epitope A, aa 121–146 | Epitope B1, aa 155–163 | ||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Consensus sequence* | N | N | E | S | F | N | W | T | G | V | T | Q | N | G | T | S | S | A | C | K | R | R | S | N | N | S | T | H | L | K | F | K | Y | P | A | |
| A/Texas/ 50/2012† | N | I | N | |||||||||||||||||||||||||||||||||
| A/GNVL/ 01/2014‡ | A | I | G | S | N | |||||||||||||||||||||||||||||||
| A/GNVL/ 05/2014§ | I | S | S | N | Y | T | ||||||||||||||||||||||||||||||
| A/GNVL/ 06/2014§ | I | S | S | N | Y | T | ||||||||||||||||||||||||||||||
| A/GNVL/ 07/2014§ | I | S | S | N | Y | T | ||||||||||||||||||||||||||||||
| A/GNVL/ 08/2014§ | I | S | S | N | Y | T | ||||||||||||||||||||||||||||||
| A/GNVL/ 09/2014¶ | I | S | S | N | Y | T | ||||||||||||||||||||||||||||||
*Yamashita et al. (9).
†Virus in 2013–14 and 2014–15 vaccines, Northern Hemisphere; GenBank accession no. KC892952.1.
‡GenBank accession no. KJ439217.
§Viruses in nasopharyngeal swabs collected in November 2014.
¶Virus in sputum collected in November 2014.
References
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- Centers for Disease Control and Prevention. CDC presents updated estimates of flu vaccine effectiveness for the 2014–2015 season [cited 10/23/2015]. http://www.cdc.gov/flu/news/updated-vaccine-effectiveness-2014-15.htm
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- World Health Organization. WHO information for molecular diagnosis of influenza virus in humans—update [cited 2014 Jun 5]. http://www.who.int/influenza/gisrs_laboratory/molecular_diagnosis_influenza_virus_humans_update_201403.pdf?ua=1
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