Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 22, Number 1—January 2016

Hemagglutinin Gene Clade 3C.2a Influenza A(H3N2) Viruses, Alachua County, Florida, USA, 2014–15

John Lednicky, Nicole M. Iovine, Joe Brew, Julia Loeb, Jonathan D. Sugimoto, Kenneth H. Rand, and J. Glenn MorrisComments to Author 
Author affiliations: University of Florida, Gainesville, Florida, USA (J.A. Lednicky, N.M. Iovine, J. Brew, J.C. Loeb, K.H. Rand, J.G. Morris, Jr.); Florida Department of Health, Gainesville (J. Brew); Fred Hutchinson Cancer Research Center, Seattle, Washington, USA (J.D. Sugimoto)

Main Article

Table 2

Estimated influenza vaccine effectiveness for children in Alachua County, Florida, USA, as compared with Florida Region 3, and Florida as a whole*

Age group, y Influenza season Region 3, % (95% CI) Florida, % (95% CI)
5–17 2012–13 71 (67–76) 73 (68–78)
2013–14 73 (68–79) 77 (72–82)

63 (58–69)
73 (68–78)
0–4 2012–13 82 (79–86) 84 (80–87)
2013–14 85 (82–89) 88 (85–91)
2014–15 80 (77–84) 86 (83–89)

*Estimates are based on reports of influenza-like illness from emergency departments reported through Florida’s Electronic Surveillance System for the Early Notification of Community-based Epidemics. See Tran et al. (11) for detailed methods. Region 3 and Florida are comparison areas, so they exclude Alachua County data.

Main Article

  1. Centers for Disease Control and Prevention. Vaccine effectiveness—how well does the flu vaccine work? [cited 2014 Nov 24].
  2. Centers for Disease Control and Prevention. Selected publications on influenza vaccine effectiveness [cited 2014 Nov 24].
  3. World Health Organization. Recommended composition of influenza virus vaccines for use in the 2014–2015 Northern Hemisphere influenza season [cited 2014 Nov 24].
  4. World Health Organization. Recommended composition of influenza virus vaccines for use in the 2015 Southern Hemisphere influenza season [cited 2014 Nov 24].
  5. Centers for Disease Control and Prevention. CDC presents updated estimates of flu vaccine effectiveness for the 2014–2015 season [cited 10/23/2015].
  6. Lednicky  JA, Loeb  JC. Detection and isolation of airborne influenza A H3N2 virus using a Sioutas Personal Cascade Impactor Sampler. Influenza Res Treat. 2013;2013:656825.
  7. World Health Organization. WHO information for molecular diagnosis of influenza virus in humans—update [cited 2014 Jun 5].
  8. European Centre for Disease Prevention and Control. Influenza virus characterization. Summary Europe, July 2014 [cited 10/23/2015].
  9. Yamashita  A, Kawashita  N, Kubota-Koketsu  R, Inoue  Y, Watanabe  Y, Ibrahim  MS, Highly conserved sequences for human neutralization epitope on hemagglutinin of influenza A viruses H3N2, H1N1, and H5N1: implication for human monoclonal antibody recognition. Biochem Biophys Res Commun. 2010;393:6148. DOIPubMedGoogle Scholar
  10. Iovine  NM, Morris  JG Jr, Fredenburg  K, Rand  K, Alnuaimat  H, Lipori  G, Increased severity of H1N1 influenza in the 2013–14 season and emergence of the D225G variant. Emerg Infect Dis. 2015;21:6647. DOIPubMedGoogle Scholar
  11. Tran  CH, Sugimoto  JD, Pilliam  JRC, Ryan  KA, Myers  PD, Castleman  JB, School-located influenza vaccine reduces community risk for influenza and influenza-like illness emergency care visits. PLoS ONE. 2014;9:e114479. DOIPubMedGoogle Scholar
  12. Tran  CH, McElrath  J, Hughes  P, Ryan  K, Munden  J, Castleman  JB, Implementing a community-supported school-based influenza immunization program. Biosecur Bioterror. 2010;8:33141. DOIPubMedGoogle Scholar
  13. Skowronski  DM, Chambers  C, Sabaiduc  S, De Serres  G, Dickinson  JA, Winter  AL, Interim estimates of 2014/15 vaccine effectiveness against influenza A(H3N2) from Canada’s Sentinel Physician Surveillance Network, January 2015. Euro Surveill. 2015;20:21022 . DOIPubMedGoogle Scholar

Main Article

Page created: December 18, 2015
Page updated: December 18, 2015
Page reviewed: December 18, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.