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Volume 22, Number 1—January 2016
Research

Multiorgan WU Polyomavirus Infection in Bone Marrow Transplant Recipient

Erica A. Siebrasse, Nang L. Nguyen, Melisa J. Willby, Dean D. Erdman, Marilyn Menegus, and David WangComments to Author 
Author affiliations: Washington University School of Medicine, St. Louis, Missouri, USA (E.A. Siebrasse, D. Wang); University of Rochester Medical Center, Rochester, New York, USA (N.L. Nguyen, M.A. Menegus); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.J. Willby, D.D. Erdman)

Main Article

Table 2

Summary of virus findings in tissue samples from child with acute respiratory illness*

Study Lung Liver Kidney Gastrointestinal
Intranuclear inclusions Positive Positive Positive Positive
Electron microscopy Positive Not performed Not performed Not performed
WUPyV/KIPyV qPCR Positive (16.6) Positive (30.8) Positive (30.4) Positive (30.2)
WUPyV PCR and sequencing Positive Positive Positive Positive
KIPyV PCR and sequencing Negative Negative Negative Negative
WUPyV IHC Positive Negative Negative Negative
HBoV qPCR Negative Negative Negative Negative

*Numbers in parentheses indicate cycle thresholds from qPCR. HBoV, human bocavirus; IHC, immunohistochemistry; KIPyV, KI polyomavirus; qPCR, real-time quantitative PCR; WUPyV, WU polyomavirus.

Main Article

Page created: December 18, 2015
Page updated: December 18, 2015
Page reviewed: December 18, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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