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Volume 22, Number 2—February 2016

Dispatch

Bordetella pertussis Strain Lacking Pertactin and Pertussis Toxin

Margaret M. WilliamsComments to Author , Kathryn Sen, Michael R. Weigand, Tami H. Skoff, Victoria A. Cunningham, Tanya A. Halse, M. Lucia Tondella, and CDC Pertussis Working Group
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.M. Williams, M.R. Weigand, T.H. Skoff, M.L. Tondella); New York State Department of Health, Albany, New York, USA (K.A. Sen); Livingston County Health Department, Mt. Morris, New York, USA (V.A. Cunningham); Wadsworth Center, Albany (T.A. Halse)

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Figure 2

Map of the 28-kb region deleted in Bordetella pertussis strains I979 and FR3749, compared with vaccine strain Tohama I. Vertical lines indicate the deletion boundaries, at a nucleotide G of the IS481 6-base insertion site motif. The deleted region is flanked by a single IS481 on each end in Tohama I and FR3749; I979 contains a second tandem IS481 downstream of the deletion. In Tohama I, IS1002 is located in the deletion region immediately upstream of IS481, and they share the 6-base motif.

Figure 2. Map of the 28-kb region deleted in Bordetella pertussis strains I979 and FR3749, compared with vaccine strain Tohama I. Vertical lines indicate the deletion boundaries, at a nucleotide G of the IS481 6-base insertion site motif. The deleted region is flanked by a single IS481 on each end in Tohama I and FR3749; I979 contains a second tandem IS481 downstream of the deletion. In Tohama I, IS1002 is located in the deletion region immediately upstream of IS481, and they share the 6-base motif.

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1Members of the CDC Pertussis Working Group are listed at the end of this article.

Page created: January 15, 2016
Page updated: January 15, 2016
Page reviewed: January 15, 2016
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