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Volume 22, Number 2—February 2016
Dispatch

Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool

Thomas HoenenComments to Author , Allison Groseth, Kyle Rosenke, Robert J. Fischer, Andreas Hoenen, Seth D. Judson, Cynthia Martellaro, Darryl Falzarano, Andrea Marzi, R. Burke Squires, Kurt R. Wollenberg, Emmie de Wit, Joseph B. Prescott, David Safronetz, Neeltje van Doremalen, Trenton Bushmaker, Friederike Feldmann, Kristin McNally, Fatorma K. Bolay, Barry Fields, Tara Sealy, Mark Rayfield, Stuart T. Nichol, Kathryn C. Zoon, Moses Massaquoi, Vincent J. Munster, and Heinz Feldmann
Author affiliations: Friedrich-Loeffler-Institut, Greifswald–Insel Riems, Germany (T. Hoenen, A. Groseth); National Institutes of Health, Hamilton, Montana, USA (T. Hoenen, A. Groseth, K. Rosenke, R.J. Fischer, S.D. Judson, C. Martellaro, D. Falzarano, A. Marzi, E. de Wit, J. Prescott, D. Safronetz, N. van Doremalen, T. Bushmaker, F. Feldmann, K. McNally, V.J. Munster, H. Feldmann); Independent scholar, Aachen, Germany (A. Hoenen); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (D. Falzarano); National Institutes of Health, Bethesda, Maryland, USA (R.B. Squires, K.R. Wollenberg, K.C. Zoon); The Liberian Institute for Biomedical Research, Charles Ville, Republic of Liberia (F.K. Bolay); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (B. Fields, T. Sealy, M. Rayfield, S.T. Nichol); Ministry of Health and Social Welfare, Monrovia, Republic of Liberia (M. Massaquoi)

Main Article

Figure 2

Observed mutations in the 8 fully nanopore-sequenced Ebola-positive blood samples compared to a reference sequence from June 2014 (SLI/Makona-EM106, GenBank accession number KM233036.1). Squares indicate nonsynonymous mutations, circles indicate synonymous changes, and triangles indicate changes in noncoding regions.

Figure 2. Observed mutations in the 8 fully nanopore-sequenced Ebola-positive blood samples compared to a reference sequence from June 2014 (SLI/Makona-EM106, GenBank accession number KM233036.1). Squares indicate nonsynonymous mutations, circles indicate synonymous changes, and triangles indicate changes in noncoding regions.

Main Article

Page created: January 15, 2016
Page updated: January 15, 2016
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