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Volume 22, Number 3—March 2016

Identification of Novel Zoonotic Activity of Bartonella spp., France

Muriel Vayssier-Taussat, Sara Moutailler, Françoise Féménia, Philippe Raymond, Olivier Croce, Bernard La Scola, Pierre-Edouard Fournier, and Didier Raoult
Author affiliations: Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail, Maisons Alfort, France (M. Vayssier-Taussat, S. Moutailler, F. Féménia); Groupe Chronimed, Saint-Péray, France (P. Raymond); Aix-Marseille Université, Marseille, France (O. Croce, B. La Scola, P-E. Fournier, D. Raoult)

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Table 4

Comparisons of 6 sequenced genomes of Bartonella spp. isolated from humans in France expressing novel zoonotic activity showing relationships to each other and to those of closely related strains

Compared genomes (GenBank accession nos.) B. henselae MVT01 B. henselae MVT02 B. henselae MVT03 B. tribocorum MVT04 B. doshiae MVT05 B. schoenbuchensis MVT07 B. henselae Houston-1 B. tribocorum CIP 105476 B. doshiae NCTC 12862 B. schoenbuchensis m07a
B. henselae MVT01 (HG965802) *100% 100% ± 0.05 92.90% ± 1.74 28.20% ± 2.43 28.10% ± 2.43 23.80% ± 2.38 98.30% ± 0.64 28.20% ± 2.43 28.00% ± 2.43 23.60% ± 2.38
B. henselae MVT02 (NZ_LN879429) 10 100% 93.00% ± 1.72 28.20% ± 2.43 28.10% ± 2.43 23.80% ± 2.39 98.30% ± 0.64 28.20% ± 2.43 28.00% ± 2.43 23.60% ± 2.38
B. henselae MVT03 (HG969191) 1,938 1,937 100% 28.00% ± 2.43 28.00% ± 2.43 23.80% ± 2.39 92.30% ± 1.82 28.00% ± 2.43 27.90% ± 2.43 23.80% ± 2.39
B. tribocorum MVT04 (HG969192–HG969193) NA NA NA 100% 26.50% ± 2.42 22.70% ± 2.37 28.20% ± 2.43 99.30% ± 0.33 26.60% ± 2.42 22.50% ± 2.36
B. doshiae MVT05 (CCBL010000001–CCBL010000013) NA NA NA NA 100% 23.60% ± 2.38 28.10% ± 2.43 26.50% ± 2.42 81.40% ± 2.72 23.60% ± 2.38
B. schoenbuchensis MVT07 (HG977193–HG977197) NA NA NA NA NA 100% 23.70% ± 2.38 22.70% ± 2.37 23.60% ± 2.38 80.30% ± 2.77
B. henselae Houston-1 (NC_005956) 693 698 2,093 NA NA NA 100% 28.20% ± 2.43 28.00% ± 2.43 23.60% ± 2.38
B. tribocorum CIP 105476 (NC_010161, NC_010160) NA NA NA 51 NA NA NA 100% 26.60% ± 2.42 22.60% ± 2.37
B. doshiae NCTC 12862 (NZ_JH725094–NZ_JH725100) NA NA NA NA >10,000 NA NA NA 100% 23.60% ± 2.38
B. schoenbuchensis m07a (NZ_KB915627–NZ_KB915629, NZ_CM001846, NZ_CM001845) NA NA NA NA NA >10,000 NA NA NA 100%

*All values are percentage identity + SD. Isolates designated MVT01–07 and MVT07 are isolates from humans in France. Gray shading indicates in silico DNA–DNA hybridization values obtained by using Genome-to-Genome Distance Calculator software (; darker shading indicates values >70%. Unshaded values are SNP numbers calculated by using SNP identification for strain typing software (23). NA, not applicable because SNP numbers cannot be estimated for distant genomes.

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