Decreased Time to Treatment Initiation for Multidrug-Resistant Tuberculosis Patients after Use of Xpert MTB/RIF Test, Latvia
Helen R. Stagg
, Peter A. White, Vija Riekstiņa, Andra Cīrule, Ģirts Šķenders, Vaira Leimane1
, Liga Kuksa1
, Gunta Dravniece, James Brown, and Charlotte Jackson
Author affiliations: University College London, London, UK (H.R. Stagg, J. Brown, C. Jackson); Medical Research Council Centre for Outbreak Analysis and Modelling, London (P.J. White); National Institute for Health Research Health Protection Research Unit in Modelling Methodology, London (P.J. White); Imperial College School of Public Health, London (P.J. White); Public Health England, London (P.J. White); University of Latvia, Riga, Latvia (V. Riekstiņa); Riga East University Hospital, Riga (V. Riekstiņa, A. Cīrule, Ģ. Šķenders, V. Leimane, L. Kuksa); KNCV Tuberculosis Foundation, The Hague, the Netherlands (G. Dravniece); Royal Free London National Health Service Trust, London (J. Brown)
Figure 1. Diagnostic pathways for patients with multidrug-resistant tuberculosis, Latvia, 2012. A) With use of Xpert MTB/RIF; B) without use of Xpert MTB/RIF. A line probe assay was used if Xpert and DST showed discordant results. MTB, Mycobacterium tuberculosis; RIF, rifampin; TB, tuberculosis; DST, drug sensitivity testing; Xpert, Xpert MTB/RIF.
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