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Volume 22, Number 4—April 2016

Evaluation of Viremia Frequencies of a Novel Human Pegivirus by Using Bioinformatic Screening and PCR

David Bonsall, William F. Gregory, Camilla L.C. Ip, Sharyne Donfield, James Iles, M. Azim Ansari, Paolo Piazza, Amy Trebes, Anthony Brown, John Frater, Oliver G. Pybus, Phillip Goulder, Paul Klenerman, Rory Bowden, Edward D. Gomperts, Eleanor Barnes, Amit Kapoor, Colin P. Sharp, and Peter SimmondsComments to Author 
Author affiliations: University of Oxford, Oxford, UK (D. Bonsall, C.L.C. Ip, J. Iles, M.A. Ansari, P. Piazza, A. Trebes, A. Brown, J. Frater, O.G. Pybus, P. Goulder, P. Klenerman, R. Bowden, E. Barnes, P. Simmonds); University of Edinburgh Easter Bush, Edinburgh, Scotland, UK (W.F. Gregory, C.P. Sharp); Rho, Inc., Chapel Hill, North Carolina, USA (S. Donfield); The Childrens' Hospital, Los Angeles, California, USA (E.D. Gomperts); The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA (A. Kapoor)

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Table 2

Detection frequencies of HPgV by sequence library screening and PCR*

Diagnostic method Diagnoses and characteristics No. tested No. (%) HHpgV-1+ No. (%) HPgV+
HIV+ 36 0 3 (8.3)
HIV+/HCV+/PWID 30 0 3 (10.0)

2 (1.7)
14 (11.6)
Hemophilia† 195 1 (0.5) 18 (9.2)
Control group‡ 50 0 1 (2.0)

*HPgV, human pegivirus; HHpgV, human hepegivirus; +, positive;HCV, hepatitis C virus; PWID, persons who inject drugs.
†Previously exposed to virally inactivated factor VIII/IX; all seropositive for HCV.
‡No history of parenteral exposure; HIV-1 and HCV negative.

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Page created: March 15, 2016
Page updated: March 15, 2016
Page reviewed: March 15, 2016
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