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Volume 22, Number 5—May 2016

Acute Human Inkoo and Chatanga Virus Infections, Finland

Niina PutkuriComments to Author , Anu Kantele, Lev Levanov, Ilkka Kivistö, Markus Brummer-Korvenkontio, Antti Vaheri, and Olli Vapalahti
Author affiliations: University of Helsinki, Helsinki, Finland (N. Putkuri, L. Levanov, I. Kivistö, M. Brummer-Korvenkontio, A. Vaheri, O. Vapalahti); Helsinki University Hospital, Helsinki (A. Kantele, A. Vaheri, O. Vapalahti)

Main Article

Table 4

Clinical progression of illness for patients hospitalized with acute INKV (n = 4) or CHATV infection (n = 2), Finland*

Virus and patient no.
Illness progression
Additional findings
1 Day 1: fever 38°C, influenza-like symptoms Elevated HHV-6 antibody levels from same sample
Day 3: disoriented
Day 6: hospitalized, abnormal EEG, CAL IgM+
Day 7: psychotic but discharged
Day 10: follow-up EEG shows same abnormalities
3 mo later: EEG almost normal
2 Day 1: fever 39.5°C, headache, nuchal rigidity, sore throat before fever, hospitalized Tick bite 1 mo earlier, erythema migrans; day 1: BorrAb neg
Day 2: nuchal rigidity, headache deteriorating, slowness but oriented
Day 3: discharged, CAL IgM+
Day 5: headache again, hospitalized
Day 6: discharged
3 Day 1: vomiting
Day 2: stomach pain, diarrhea, seizures,  hospitalized
Day 3: fever 38.3°C, drowsiness, convulsions
Day 4: More seizures, small changes in EEG
Day 5: CAL IgM+
Day 8: discharged
4 Day 1: fever 37.9°C, sore throat Tick bite 3 wks earlier
Day 3: CAL IgM+
Day 4: nausea and vomiting
Day 5: fever 39°C, headache, nuchal rigidity, hospitalized

Day 10: recovered and discharged

1 Day 1: vomiting continuing for 3 d
Day 4: fever, hospitalized, disoriented at night
Day 7: frontal headache, normal head CT and abdominal ultrasound
Day 12: discharged, CAL IgM+
2 Day 1: fever 39°C, back pain Back injury 2 wks earlier
Day 7: hospitalized, high fever, back pain almost resolved
Day 7–22: temporal pain, trembling of hands, fluctuating fever
Day 17: CAL IgM+
Day 23: discharged

*BorrAb, Borrelia antibody test; CHATV, Chatanga virus; CT, computer tomographic scan; EEG, electroencephalogram; HHV, human herpesvirus; INKV, Inkoo virus. CAL IgM+ indicates the day when IgM for California encephalitis group viruses was observed.

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Page created: April 13, 2016
Page updated: April 13, 2016
Page reviewed: April 13, 2016
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