Volume 22, Number 5—May 2016
Research
Acute Human Inkoo and Chatanga Virus Infections, Finland
Table 4
Clinical progression of illness for patients hospitalized with acute INKV (n = 4) or CHATV infection (n = 2), Finland*
Virus and patient no. |
Illness progression |
Additional findings |
INKV | ||
1 | Day 1: fever 38°C, influenza-like symptoms | Elevated HHV-6 antibody levels from same sample |
Day 3: disoriented | ||
Day 6: hospitalized, abnormal EEG, CAL IgM+ | ||
Day 7: psychotic but discharged | ||
Day 10: follow-up EEG shows same abnormalities | ||
3 mo later: EEG almost normal | ||
2 | Day 1: fever 39.5°C, headache, nuchal rigidity, sore throat before fever, hospitalized | Tick bite 1 mo earlier, erythema migrans; day 1: BorrAb neg |
Day 2: nuchal rigidity, headache deteriorating, slowness but oriented | ||
Day 3: discharged, CAL IgM+ | ||
Day 5: headache again, hospitalized | ||
Day 6: discharged | ||
3 | Day 1: vomiting | |
Day 2: stomach pain, diarrhea, seizures, hospitalized | ||
Day 3: fever 38.3°C, drowsiness, convulsions | ||
Day 4: More seizures, small changes in EEG | ||
Day 5: CAL IgM+ | ||
Day 8: discharged | ||
4 | Day 1: fever 37.9°C, sore throat | Tick bite 3 wks earlier |
Day 3: CAL IgM+ | ||
Day 4: nausea and vomiting | ||
Day 5: fever 39°C, headache, nuchal rigidity, hospitalized | ||
Day 10: recovered and discharged |
||
CHATV | ||
1 | Day 1: vomiting continuing for 3 d | |
Day 4: fever, hospitalized, disoriented at night | ||
Day 7: frontal headache, normal head CT and abdominal ultrasound | ||
Day 12: discharged, CAL IgM+ | ||
2 | Day 1: fever 39°C, back pain | Back injury 2 wks earlier |
Day 7: hospitalized, high fever, back pain almost resolved | ||
Day 7–22: temporal pain, trembling of hands, fluctuating fever | ||
Day 17: CAL IgM+ | ||
Day 23: discharged |
*BorrAb, Borrelia antibody test; CHATV, Chatanga virus; CT, computer tomographic scan; EEG, electroencephalogram; HHV, human herpesvirus; INKV, Inkoo virus. CAL IgM+ indicates the day when IgM for California encephalitis group viruses was observed.