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Volume 22, Number 5—May 2016

Outbreak of Middle East Respiratory Syndrome at Tertiary Care Hospital, Jeddah, Saudi Arabia, 2014

Deborah L. Hastings1, Jerome I. Tokars1, Inas Zakaria A.M. Abdel Aziz, Khulud Z. Alkhaldi, Areej T. Bensadek, Basem M. Alraddadi, Hani Jokhdar, John A. Jernigan, Mohammed A. Garout2, Sara M. Tomczyk, Ikwo K. Oboho, Andrew I. Geller, Nimalan Arinaminpathy, David L. Swerdlow3, and Tariq A. MadaniComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (D.L. Hastings, J.I. Tokars, J.A. Jernigan, S.M. Tomczyk, I.K. Oboho, A.I. Geller, D.L. Swerdlow); Cairo University, Cairo, Egypt (I.Z.A.M. Abdel Aziz); Ministry of Health, Jeddah, Saudi Arabia (K.Z. Alkhaldi, T.A. Madani); King Fahd General Hospital, Jeddah (A.T. Bensadek, H. Jokhdar, M.A. Garout); King Faisal Specialist Hospital and Research Center, Jeddah (B.M. Alraddadi); Central Board of Accreditation for Healthcare Institutions, Jeddah (H. Jokhdar); Umm Al-Qura University, Makkah, Saudi Arabia (H. Jokhdar, M.A. Garout); International Medical Center, Jeddah (M.A. Garout); Imperial College of London, London, UK (N. Arinaminpathy); King Abulaziz University, Jeddah (T.A. Madani)

Main Article

Table 2

Calculation of most probable setting of Middle East respiratory syndrome coronavirus acquisition for a patient with onset date April 2, 2014, King Fahd General Hospital, Jeddah, Saudi Arabia*

Date Setting where treated Incubation period, d Probability
Mar 24 ED 9† 0.0578‡
Mar 25 ED 8 0.0396§
Mar 25 Inpatient 8 0.0396§
Mar 26 Dialysis 7 0.0530
Mar 26 Inpatient 7 0.0530
Mar 27 Inpatient 6 0.1358
Mar 28 Dialysis 5 0.0800
Mar 29 Inpatient 5 0.0800
Mar 29 Dialysis 4 0.0803
Mar 29 Inpatient 4 0.0803
Mar 30 Inpatient 3 0.1141

*Data are from patient 5 (Figure 1). The total probability is 0.50 for inpatient, 0.21 for the dialysis unit, and 0.10 for ED, so acquisition most probably occurred in the inpatient areas. ED, emergency department.
†Represents the incubation period if date of disease acquisition was March 24 and disease onset was April 2.
‡Represents the probability of an incubation period of 9 days (Table 1).
§Patient was treated in 2 settings on March 25, so probability is half of the probability for each setting.

Main Article

1These authors contributed equally to this article.

2Current affiliation: International Medical Center, Jeddah, Saudi Arabia.

3Current affiliation: Pfizer Inc., Collegeville, Pennsylvania, USA.

Page created: April 13, 2016
Page updated: April 13, 2016
Page reviewed: April 13, 2016
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