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Volume 22, Number 8—August 2016
Research

Phylogeographic Evidence for 2 Genetically Distinct Zoonotic Plasmodium knowlesi Parasites, Malaysia

Ruhani Yusof1, Md Atique Ahmed1, Jenarun Jelip, Hie Ung Ngian, Sahlawati Mustakim, Hani Mat Hussin, Mun Yik Fong, Rohela Mahmud, Frankie Anak Thomas Sitam, J. Rovie-Ryan Japning, Georges Snounou, Ananias A. Escalante, and Yee Ling LauComments to Author 
Author affiliations: University of Malaya Faculty of Medicine, Kuala Lumpur, Malaysia (R. Yusof, M.A. Ahmed, M.Y. Fong, R. Mahmud, Y.L. Lau); Sabah State Health Department, Sabah, Malaysia (J. Jelip); Hospital Kapit, Sarawak, Malaysia (H.U. Ngian); Hospital Tengku Microbiology Laboratory, Ampuan Rahimah, Selangor, Malaysia (S. Mustakim); Kelantan State Health Department, Kelantan, Malaysia (H.M. Hussin); Department of Wildlife and National Parks Peninsular Malaysia, Kuala Lumpur, Malaysia (F.A.T. Sitam, J. Rovie-Ryan); Sorbonne Universités, INSERM, Paris, France (G. Snounou); Temple University, Philadelphia, PA, USA (G. Snounou, A.A. Escalante)

Main Article

Figure 5

Most likely number of Plasmodium knowlesi parasite subpopulation haplotype clusters (K) in Malaysian Borneo (gray) and Peninsular Malaysia (white). A) Type A small subunit ribosomal 18S RNA (K = 2, ΔK = 121.79), including comparison of K and ΔK; B) cytochrome oxidase subunit I (K = 2, ΔK = 481.27), including comparison between K and ΔK. Relationships were determined by using Bayesian model–based STRUCTURE version 2.3.4 software (The Pritchard Laboratory, Stanford University, Stanford, CA, SUA).

Figure 5. Most likely number of Plasmodium knowlesi parasite subpopulation haplotype clusters (K) in Malaysian Borneo (gray) and Peninsular Malaysia (white). A) Type A small subunit ribosomal 18S RNA (K = 2, ΔK = 121.79), including comparison of K and ΔK; B) cytochrome oxidase subunit I (K = 2, ΔK = 481.27), including comparison between K and ΔK. Relationships were determined by using Bayesian model–based STRUCTURE version 2.3.4 software (The Pritchard Laboratory, Stanford University, Stanford, CA, SUA). ΔK = mean (|L′′(K)|)/sd(L(K)). Vertical axes represent membership coefficient values.

Main Article

1These authors contributed equally to this article.

Page created: July 15, 2016
Page updated: July 15, 2016
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