Volume 22, Number 9—September 2016
Dispatch
Nosocomial Outbreak of Parechovirus 3 Infection among Newborns, Austria, 2014
Volker Strenger
, Sabine Diedrich, Sindy Boettcher, Susanne Richter, Peter Maritschnegg, Dietmar Gangl, Simone Fuchs, Gernot Grangl, Bernhard Resch, and Berndt Urlesberger
, Sabine Diedrich, Sindy Boettcher, Susanne Richter, Peter Maritschnegg, Dietmar Gangl, Simone Fuchs, Gernot Grangl, Bernhard Resch, and Berndt Urlesberger
Table
Clinical characteristics for 9 newborns with human parechovirus 3 infection, Austria, 2014*
| Characteristic | No. (%) patients | Median (range)† |
|---|---|---|
| Demographic | ||
| Male sex | 5 (55.6) | NA |
| Gestational age, wk + d | NA | 40 + 1 (38 + 3 to 41 + 2) |
| Birth weight, g | NA | 3,480 (3,240–4,160) |
| Vaginal delivery | 6 (66.7) | |
| Age at onset of fever, d | NA | 6 (1–27) |
| Age at admission to PD, d | NA | 6 (2–27) |
| Time from discharge from maternity to admission to PD, d | NA | 1 (0–24) |
| Clinical | ||
| Fever | 9 (100) | 39.1°C (38.5°C–39.9°C) |
| Reduced general condition | 4 (44.4) | NA |
| Tachypnea | 4 (44.4) | NA |
| Tachycardia | 3 (33.3) | NA |
| Drinking difficulties | 5 (55.6) | NA |
| Circulatory centralization | 3 (33.3) | NA |
| Increased irritability | 3 (33.3) | NA |
| Treatment | ||
| Admission to NICU or PICU | 3 (33.3) | NA |
| Antimicrobial drug treatment (cefuroxime + amoxicillin) | 8 (88.9) | 3 (2−5) d |
| Intravenous hydration | 4 (44.4) | NA |
| Length of stay at PD, d | NA | 3 (0−9) |
| Laboratory values | ||
| Leukocytes, cells/μL | NA | 7,690 (4,750–18,310) |
| Granulocytes, cells/μL | NA | 4,595 (1,300–10,124) |
| Lymphocytes, cells/μL | NA | 2,330 (590–7,100) |
| Lymphopenia, <2,000 cells/μL | 4 (44.4) | NA |
| Monocytes, cells/μL | NA | 1,100 (660–2,470) |
| Minimal thrombocytes/μL | NA | 200,000 (101,000–270,000) |
| C-reactive protein, mg/L‡ | NA | 1.6 (<0.6–11.4) |
| C-reactive protein >5 mg/L | 2 (22.2) | NA |
| Procallcitonin, ng/mL§ | NA | 0.18, 0.18, and 0.36 |
| Interleukin-6, pg/mL¶ | NA | 21.0 and 124.8 |
*NA, not applicable; NICU, neonatal intensive care unit; PD, pediatric department; PICU, pediatric intensive care unit.
†Unless otherwise indicated.
‡Upper limit of reference range = 5.0 mg/L.
§Upper limit of reference range = 0.5 ng/mL; measured for 3 patients.
¶Upper limit of reference range = 7.0 pg/m; measured for 2 patients.
Page created: August 16, 2016
Page updated: August 16, 2016
Page reviewed: August 16, 2016
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