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Volume 22, Number 9—September 2016
Dispatch

Nosocomial Outbreak of Parechovirus 3 Infection among Newborns, Austria, 2014

Volker StrengerComments to Author , Sabine Diedrich, Sindy Boettcher, Susanne Richter, Peter Maritschnegg, Dietmar Gangl, Simone Fuchs, Gernot Grangl, Bernhard Resch, and Berndt Urlesberger
Author affiliations: Medical University of Graz, Graz, Austria (V. Strenger, P. Maritschnegg, S. Fuchs, G. Grangl, B. Resch, B. Urlesberger); Robert Koch-Institute, Berlin, Germany (S. Diedrich, S. Boettcher); Institute for Veterinary Disease Control, Mödling, Austria (S. Richter); Regional Hospital Feldbach, Feldbach, Austria (D. Gangl)

Main Article

Table

Clinical characteristics for 9 newborns with human parechovirus 3 infection, Austria, 2014*

Characteristic No. (%) patients Median (range)†
Demographic
Male sex 5 (55.6) NA
Gestational age, wk + d NA 40 + 1 (38 + 3 to 41 + 2)
Birth weight, g NA 3,480 (3,240–4,160)
Vaginal delivery 6 (66.7)
Age at onset of fever, d NA 6 (1–27)
Age at admission to PD, d NA 6 (2–27)
Time from discharge from maternity to admission to PD, d NA 1 (0–24)
Clinical
Fever 9 (100) 39.1°C (38.5°C–39.9°C)
Reduced general condition 4 (44.4) NA
Tachypnea 4 (44.4) NA
Tachycardia 3 (33.3) NA
Drinking difficulties 5 (55.6) NA
Circulatory centralization 3 (33.3) NA
Increased irritability 3 (33.3) NA
Treatment
Admission to NICU or PICU 3 (33.3) NA
Antimicrobial drug treatment (cefuroxime + amoxicillin) 8 (88.9) 3 (2−5) d
Intravenous hydration 4 (44.4) NA
Length of stay at PD, d NA 3 (0−9)
Laboratory values
Leukocytes, cells/μL NA 7,690 (4,750–18,310)
Granulocytes, cells/μL NA 4,595 (1,300–10,124)
Lymphocytes, cells/μL NA 2,330 (590–7,100)
Lymphopenia, <2,000 cells/μL 4 (44.4) NA
Monocytes, cells/μL NA 1,100 (660–2,470)
Minimal thrombocytes/μL NA 200,000 (101,000–270,000)
C-reactive protein, mg/L‡ NA 1.6 (<0.6–11.4)
C-reactive protein >5 mg/L 2 (22.2) NA
Procallcitonin, ng/mL§ NA 0.18, 0.18, and 0.36
Interleukin-6, pg/mL¶ NA 21.0 and 124.8

*NA, not applicable; NICU, neonatal intensive care unit; PD, pediatric department; PICU, pediatric intensive care unit.
†Unless otherwise indicated.
‡Upper limit of reference range = 5.0 mg/L.
§Upper limit of reference range = 0.5 ng/mL; measured for 3 patients.
¶Upper limit of reference range = 7.0 pg/m; measured for 2 patients.

Main Article

Page created: August 16, 2016
Page updated: August 16, 2016
Page reviewed: August 16, 2016
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