Sabine M.G. van der Sanden
, Gerrit Koen, Hetty van Eijk, Sylvie M. Koekkoek, Menno D. de Jong, and Katja C. Wolthers
Figure 4. Amino acid sequence comparison of the capsid regions of EV-71 strains used for serologic analysis of strains isolated in Asia and Europe in study of immunity to these strains after exposure to IVIg from viruses from the Netherlands. Residues 164, 240, and 241 of VP1 (differing among genogroup B and C viruses and located in known antigenic sites) and residues that differ among neutralizable and nonneutralizable strains are marked by boxes. Known epitopes and antigenic determinants for EV-71 are marked in gray (22–25). EV-71, enterovirus 71; IVIg, intravenous immunoglobulin; VN, Vietnam; VP, viral protein.