Volume 22, Number 9—September 2016
Research
Prediction of Protection against Asian Enterovirus 71 Outbreak Strains by Cross-neutralizing Capacity of Serum from Dutch Donors, The Netherlands
Sabine M.G. van der Sanden
, Gerrit Koen, Hetty van Eijk, Sylvie M. Koekkoek, Menno D. de Jong, and Katja C. Wolthers
, Gerrit Koen, Hetty van Eijk, Sylvie M. Koekkoek, Menno D. de Jong, and Katja C. Wolthers
Table 1
Percentages of children <5 y of age, women of childbearing age, and HIV-positive men with nAb titers against the Dutch enterovirus 71 strain C1 91–480, the Netherlands*
| Year |
No. positive/no. tested (%, 95% CI) |
||||||
| Children, age, y |
Adults, characteristics |
||||||
| <0.5 |
0.5–2 |
>2–5 |
Total ≤5 |
F, childbearing age |
M, HIV-positive |
||
| 2010 |
1/1
(100, 20.6–100) |
0/7
(0, 0–35.4) |
3/5
(60.0, 23.1–88.2) |
4/13
(30.8, 12.7–57.6) |
10/13
(76.9, 49.7–91.8) |
9/14
(64.3, 38.8–83.7) |
|
| 2011 |
1/2
(50.0, 9.5–90.6) |
4/7
(57.1, 25.0–84.2) |
3/6
(50.0, 18.8–81.2) |
8/15
(53.3, 30.1–75.2) |
8/10
(80.0, 49.0–94.3) |
5/10
(50.0, 23.7–76.3) |
|
| 2012 |
0/0 |
1/8
(12.5, 2.2–47.1) |
5/6
(83.3, 43.7–97.0) |
6/14
(42.9, 21.4–67.4) |
9/12
(75.0, 46.8–91.1) |
10/14
(71.4, 45.4–88.3) |
|
| 2013 |
0/0 |
1/3
(33.3, 6.2–79.2) |
4/8
(50.0, 21.5–78.5) |
5/11
(45.5, 21.3–71.2) |
6/8
(75.0, 40.9–92.9) |
10/14
(71.4, 45.4–88.3) |
|
| 2014 |
0/0 |
0/5
(0, 0.0–43.5) |
2/3
(66.7, 20.8–93.9) |
2/8
(25.0, 7.2–59.1) |
11/13
(84.6, 57.8–95.7) |
5/8
(62.5, 30.6–86.3) |
|
| Total |
2/3
(66.7, 20.8–93.9) |
6/30
(20.0, 9.5–37.3) |
17/28
(60.7, 42.4–76.4) |
25/61
(41.0, 29.5–53.5) |
44/56
(78.6, 66.2–87.3) |
39/60
(65.0, 52.4–75.8) |
|
| *nAb, neutralizing antibody. | |||||||
Page created: August 16, 2016
Page updated: August 16, 2016
Page reviewed: August 16, 2016
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