Volume 23, Number 2—February 2017
Dispatch
Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
Hiroyuki Okada
, Yoshifumi Iwamaru, Morikazu Imamura, Kohtaro Miyazawa, Yuichi Matsuura, Kentaro Masujin, Yuichi Murayama, and Takashi Yokoyama
, Yoshifumi Iwamaru, Morikazu Imamura, Kohtaro Miyazawa, Yuichi Matsuura, Kentaro Masujin, Yuichi Murayama, and Takashi Yokoyama
Table
Experimental oral inoculation of 16 calves with brain homogenate of L-type bovine spongiform encephalopathy prions*
| Inoculum dose, g | No. inoculated | No. died (postinoculation mo) | No. euthanized (postinoculation mo) |
|---|---|---|---|
| 1 | 4 | 0 | 2 (51), 2 (52) |
| 5 | 6 | 0 | 1 (54), 2 (70), 1 (73), 1 (75), 1 (82) |
| 10 | 4 | 0 | 1 (74), 1 (81), 1 (85), 1 (86) |
| 50 | 2 | 1 (88) | 0 |
*Necropsies were performed on all animals except the 1 still alive as of December 2016.
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