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Volume 23, Number 2—February 2017
CME ACTIVITY - Research

Multidrug-Resistant Candida haemulonii and C. auris, Tel Aviv, Israel

Ronen Ben-AmiComments to Author , Judith Berman, Ana Novikov, Edna Bash, Yael Shachor-Meyouhas, Shiri Zakin, Yasmin Maor, Jalal Tarabia, Vered Schechner, Amos Adler, and Talya Finn
Author affiliations: Tel Aviv University, Tel Aviv, Israel (R. Ben-Ami, J. Berman, S. Zakin, Y. Maor, V. Schechner, A. Adler); Tel Aviv Sourasky Medical Center, Tel Aviv (R. Ben-Ami, A. Novikov, E. Bash, J. Tarabia, V. Schechner, A. Adler, T. Finn); Ruth Rappaport Children's Hospital, Haifa, Israel (Y. Shachor-Meyouhas); Wolfson Medical Center, Holon, Israel (Y. Maor).

Main Article

Table 1

Characteristics of 9 patients with Candida isolates available for microbiological analyses, Tel Aviv, Israel*

Isolate ID GenBank accession nos.
 DNA sequence analysis Patient age, y/sex Hospital/unit Date Comorbidities Culture source Clinical significance Treatment In-hospital outcome
ITS LSU
TA001-14 KU896955 KU886685 C. haemulonii 52/M TASMC/vascular clinic 2014 Jun CIDP, steroids, CLU Wound Colonization None Survival
TA001-15 KU896954 KU886684 C. haemulonii 79/M TASMC/vascular clinic 2015 Apr PVD, CKD, DMt2, IHD, pacemaker, CLU Wound Colonization None Survival
TA004-15 KU896956 KU896947 C. haemulonii 69/M TASMC/vascular surgery 2015 Jun PVD, DMt2, IHD, CLU Wound Colonization None Survival
TA003-14 KU896949 KU886679 C. auris 91/F TASMC/medicine 2014 May ANCA vasculitis, M-vent, VAP, steroids, CVC Blood CRBSI Fluconazole Death
TA002-14 KX518348 KU886682 C. auris 79/M TASMC/neurosurgery 2014 Oct MDS, ASDH, M-vent, VAP; CVC Blood CRBSI CVC removed; none Death
TA004-14 KU896950 KU886680 C. auris 74/M TASMC/medicine 2014 Aug CKD, hemodialysis, CVC, pacemaker, IHD, DMt2 Blood CRBSI CVC removed; anidulafungin Survival
TA005-14 KU896951 KU886681 C. auris 57/F TASMC/medicine 2014 May PBC Blood Primary candidemia Fluconazole; anidulafungin Survival
TA003-15 KU896953 KU886683 C. auris 42/M WMC/medicine 2015 Apr IVDU, HIV, HBV, HCV, MRSA sepsis Blood Primary candidemia Fluconazole; voriconazole Survival
TA002-15 KU896948 KU886678 C. auris 79/M TASMC/medicine 2015 Apr CKD, DMt2, IHD, PICC Urine Asymptomatic candiduria None Survival

*CIDP, chronic inflammatory demyelinating polyneuropathy; CKD, chronic kidney disease; CLU, chronic leg ulcers; CRBSI, catheter-related bloodstream infection; CVC, central venous catheter; DMt2, diabetes mellitus type 2; HBV, hepatitis B virus infection; HCV, hepatitis C virus infection; IHD, ischemic heart disease; ITS, internal transcribed spacer; IVDU, intravenous drug user; LSU, large subunit; MRSA, multidrug-resistant Staphylococcus aureus; M-vent, mechanical ventilation; PBC, primary biliary cirrhosis; PICC, peripherally inserted central catheter; PVD, peripheral vascular disease; TASMC, Tel Aviv Sourasky Medical Center; VAP, ventilator-associated pneumonia; WMC, Wolfson Medical Center.

Main Article

Page created: January 12, 2017
Page updated: January 12, 2017
Page reviewed: January 12, 2017
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