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Volume 23, Number 4—April 2017

Characterization of Highly Pathogenic Avian Influenza Virus A(H5N6), Japan, November 2016

Masatoshi Okamatsu1, Makoto Ozawa1, Kosuke Soda1, Hiroki Takakuwa1, Atsushi Haga, Takahiro Hiono, Aya Matsuu, Yuko Uchida, Ritsuko Iwata, Keita Matsuno, Masakazu Kuwahara, Toshiyo Yabuta, Tatsufumi Usui, Hiroshi Ito, Manabu Onuma, Yoshihiro SakodaComments to Author , Takehiko Saito, Koichi Otsuki, Toshihiro Ito, and Hiroshi Kida
Author affiliations: Hokkaido University, Sapporo Japan (M. Okamatsu, T. Hiono, K. Matsuno, Y. Sakoda, H. Kida); Kagoshima University, Kagoshima, Japan (M. Ozawa, A. Matsuu); University, Yamaguchi, Japan (M. Ozawa, A. Matsuu); Tottori University, Tottori, Japan (K. Soda, T. Usui, H. Ito, K. Otsuki, T. Ito); Kyoto Sangyo University, Kyoto, Japan (H. Takakuwa, T. Yabuta, K. Otsuki); Matsuoka Research Institute for Science, Koganei, Tokyo, Japan (M. Kuwahara); National Agriculture and Food Research Organization, Tsukuba (Y. Uchida, T. Saito); National Institute for Environmental Studies, Tsukuba, Japan (A. Haga, R. Iwata, M. Onuma)

Main Article

Table 2

Antigenic analyses of H5 influenza viruses with antiserum*

Virus lineage/clade
Hemagglutination inhibition titers of the antiserum
Mal/Hok (H5N1)
Ws/Hok (H5N1)
Pf/HK (H5N1)
Ck/Kum (H5N8)
B. swan/ Akita (H5N6)
Ck/Yam (H5N1)
Ck/Ibr (H5N2)
Mal/Hok/24/2009 (H5N1)† 1,280 80 40 1,280 16 1,280 1,280 Ws/Hok/1/2008 (H5N1) 40 640 40 640 8 640 <20
2.3.4 Pf/HK/810/2009 (H5N1) <20 20 2,560 20 8 80 <20 icA Ck/Kumamoto/1-7/2014 (H5N8) 20 20 320 640 16 80 <20 B. swan/Akita/1/2016 (H5N6) <20 <20 80 160 256 80 <20
Ck/Yamaguchi/7/2004 (H5N1)
North American Ck/Ibaraki/1/2005 (H5N2) 320 20 <20 <20 16 1,280 20,480

*Dash indicates virus does not belong to clade classification. Bold indicates virus isolated in this study. Underline indicates homologous titers. B. swan, black swan; Ck, chicken; HK, Hong Kong; Hok, Hokkaido; Mal, mallard; Pf, peregrine falcon; Ws, whooper swan.
†Low pathogenic avian influenza viruses isolated from mallard (15) and chicken in Japan.

Main Article

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1These authors contributed equally to this article.

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