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Volume 23, Number 5—May 2017
Research

Population Genomics of Legionella longbeachae and Hidden Complexities of Infection Source Attribution

Rodrigo Bacigalupe, Diane Lindsay, Giles Edwards, and J. Ross FitzgeraldComments to Author 
Author affiliations: The Roslin Institute, University of Edinburgh, Midlothian, Scotland, UK (R. Bacigalupe, J.R. Fitzgerald); Glasgow Royal Infirmary, Glasgow, Scotland, UK (D. Lindsay, G. Edwards)

Main Article

Figure 4

Variation in gene content between environmental and patient Legionella longbeachae samples. A) Increase in pangenome size with every addition of a L. longbeachae genome. Environmental isolates pangenomes (green) are larger and continue increasing after the addition of 5 genomes, consistent with an open pangenome, but the within-patient pangenome plateaus quickly, consistent with a more closed pangenome. B) Average gene content of environmental isolates is significantly higher than that of clinic

Figure 4. Variation in gene content between environmental and patient Legionella longbeachae samples. A) Increase in pangenome size with every addition of a L. longbeachae genome. Environmental isolates pangenomes (green) are larger and continue increasing after the addition of 5 genomes, consistent with an open pangenome, but the within-patient pangenome plateaus quickly, consistent with a more closed pangenome. B) Average gene content of environmental isolates is significantly higher than that of clinical isolates (p = 0.01474).

Main Article

Page created: April 14, 2017
Page updated: April 14, 2017
Page reviewed: April 14, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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