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Volume 24, Number 1—January 2018
Research

Drug-Resistant Polymorphisms and Copy Numbers in Plasmodium falciparum, Mozambique, 2015

Himanshu Gupta, Eusebio Macete, Helder Bulo, Crizolgo Salvador, Marian Warsame, Eva Carvalho, Didier Ménard, Pascal Ringwald, Quique Bassat, Sonia Enosse1, and Alfredo Mayor1Comments to Author 
Author affiliations: ISGlobal, Barcelona Institute for Global Health Hospital Clínic, Universitat de Barcelona, Barcelona, Spain (H. Gupta, Q. Bassat, A. Mayor); Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique (E. Macete, H. Bulo, Q. Bassat, A. Mayor); Instituto Nacional de Saúde, Ministério da Saúde, Maputo (C. Salvador, S. Enosse); World Health Organization Global Malaria Programme, Geneva, Switzerland (M. Warsame, P. Ringwald); World Health Organization, Maputo (E. Carvalho); Malaria Molecular 16 Epidemiology Unit, Institut Pasteur du Cambodge, Phnom Penh, Cambodia (D. Ménard); Institut Pasteur, Paris, France (D. Ménard); ICREA, Barcelona (Q. Bassat); Pediatrics Department, Hospital Sant Joan de Déu (University of Barcelona); Barcelona, Spain (Q. Bassat)

Main Article

Table 1

Characteristics of study participants with Plasmodium falciparum malaria, by site, Mozambique, 2015

Characteristic Montepuez, n = 87 Dondo, n = 88 Moatize, n = 89 Chokwe, n = 88 p value
Female, no. (%) 36 (41.4) 40 (45.5) 41 (46.1) 42 (47.7) 0.63
Age, y, mean ± SD 2.4 ± 1.1 2.7 ± 1.1 2.7 ± 1.1 3.1 ± 1.1 0.0002
Temperature, °C, mean ± SD 37.9 ± 0.9 38.5 ± 1.1 38.1 ± 1.0 37.9 ± 1.5 0.0043
Parasite density, parasites/μL, mean ± SD* 1.2 × 105 ± 1.3 × 105 3.7 × 104 ± 4.4 × 104 1.2 × 105 ± 6.1 × 105 1.2 × 105 ± 1.8 × 105 <0.0001
Hemoglobin, g/dL, mean ± SD 8.9 ± 2.2 8.7 ± 1.8 9.8 ± 1.7 9.2 ± 2.0 0.0018

*By quantitative PCR.

Main Article

1These authors contributed equally to this article.

Page created: December 19, 2017
Page updated: December 19, 2017
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