Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 24, Number 1—January 2018

Drug-Resistant Polymorphisms and Copy Numbers in Plasmodium falciparum, Mozambique, 2015

Himanshu Gupta, Eusebio Macete, Helder Bulo, Crizolgo Salvador, Marian Warsame, Eva Carvalho, Didier Ménard, Pascal Ringwald, Quique Bassat, Sonia Enosse1, and Alfredo Mayor1Comments to Author 
Author affiliations: ISGlobal, Barcelona Institute for Global Health Hospital Clínic, Universitat de Barcelona, Barcelona, Spain (H. Gupta, Q. Bassat, A. Mayor); Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique (E. Macete, H. Bulo, Q. Bassat, A. Mayor); Instituto Nacional de Saúde, Ministério da Saúde, Maputo (C. Salvador, S. Enosse); World Health Organization Global Malaria Programme, Geneva, Switzerland (M. Warsame, P. Ringwald); World Health Organization, Maputo (E. Carvalho); Malaria Molecular 16 Epidemiology Unit, Institut Pasteur du Cambodge, Phnom Penh, Cambodia (D. Ménard); Institut Pasteur, Paris, France (D. Ménard); ICREA, Barcelona (Q. Bassat); Pediatrics Department, Hospital Sant Joan de Déu (University of Barcelona); Barcelona, Spain (Q. Bassat)

Main Article

Table 4

Distribution of Plasmodium falciparum pfdhps gene polymorphism (mutated allele) frequencies among 4 sentinel sites, Mozambique, 2015*

SNP Montepuez, no. (%) Chokwe, no. (%) Moatize, no. (%) Dondo, no. (%) p value
S436F/C/A/H 30 (34.5) 2 (2.4) 0 0 <0.0001
A437G 51 (58.6) 79 (94.1) 82 (93.2) 77 (89.5) <0.0001
K540E 50 (57.5) 77 (90.6) 83 (93.3) 76 (87.4) <0.0001
A437G + K540E
47 (54.1)
77 (91.7)
80 (90.9)
76 (88.4)
*SNP, single-nucleotide polymorphism.

Main Article

1These authors contributed equally to this article.

Page created: December 19, 2017
Page updated: December 19, 2017
Page reviewed: December 19, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.