Volume 24, Number 10—October 2018
Dispatch
Emerging Enteroviruses Causing Hand, Foot and Mouth Disease, China, 2010–2016
Table
Test result |
2013, no. (%) | 2015, no. (%) | |||
---|---|---|---|---|---|
Mild, n = 87,226 |
Severe, n = 3,837 |
Mild, n = 99,461 |
Severe, n = 4,712 |
||
EV negative | 32,801 (37.60) | 1,100 (28.67) | 35,167 (35.36) | 1,273 (27.02) | |
EV-A71 | 15,503 (17.77) | 1,557 (40.58) | 11,800 (11.86) | 1,352 (28.69) | |
CV-A16 | 10,811 (12.39) | 197 (5.13) | 13,959 (14.03) | 265 (5.62) | |
Other enteroviruses | 28,111 (32.23) | 983 (25.62) | 38,535 (38.74) | 1,822 (38.67) | |
Further serotyping of other enteroviruses | |||||
Total | Mild, n = 3,260† | Severe, n = 42‡ | Mild, n = 2,474§ | Severe, n = 71¶ | |
CV-A6 | 2,620 (80.37) | 28 (66.67) | 1,471 (59.46) | 31 (43.70) | |
CV-A10 | 176 (5.40) | 4 (9.52) | 104 (4.20) | # | |
CV-A2 | 22 (0.67) | 1 (2.38) | 5 (0.20) | # | |
CV-A5 | 9 (0.28) | 1 (2.38) | 2 (0.08) | # | |
CV-A4 | 2 (0.06) | # | 9 (0.36) | # | |
ECV-6 | 9 (0.28) | # | # | # | |
CV-B4 | 13 (0.4) | # | # | # | |
ECV-25 | 8 (0.25) | # | # | # | |
CV-A12 | 5 (0.15) | # | # | # | |
CV-B5 | 5 (0.15) | # | # | # | |
CV-B2 | 4 (0.12) | # | 1 (0.04) | # | |
ECV-7 | 4 (0.12) | # | # | # | |
ECV-9 | 3 (0.09) | # | # | # | |
CV-A8 | 1 (0.03) | # | 3 (0.12) | # | |
CV-A14 | 2 (0.06) | # | # | # | |
CV-A21 | 2 (0.06) | # | # | # | |
ECV-12 | 2 (0.06) | # | # | # | |
CV-B1 | 2 (0.06) | # | # | # | |
ECV-30 | 1 (0.03) | # | 1 (0.04) | # | |
Other | 6 (0.18)** | # | # | # | |
Untyped | 364 (11.37) | 8 (19.05) | 878 (35.49) | 40 (56.34) |
*CV, coxsackievirus; ECV, echovirus; EV, enterovirus.
†Results are based on data from Beijing, Fujian, Guangdong, Guangxi, Heilongjiang, Henan, Hubei, Jiangsu, Jilin, Shanxi, Sichuan, Shandong, Tianjin, Xinjiang, and Yunnan provinces.
‡Results are based on data from Fujian, Guangdong, Guangxi, Henan, and Shanxi provinces.
§Results are based on data from Beijing, Fujian, Guangxi, Heilongjiang, Jiangsu, Sichuan, Tianjin, and Zhejiang provinces.
¶Results are based on data from Guangdong and Jiangsu provinces.
#The serotypes were not detected, but might be included in the untyped specimens because of laboratory capacity restrictions.
**Other serotypes include CV-A20, CV-A24, ECV-1, ECV-96, Polio1, and Polio2, with 1 of each serotype detected.
1These authors contributed equally to this article.
2Current affiliation: Fudan University School of Public Health, Shanghai, China.