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Volume 24, Number 10—October 2018
Research

Zika Virus Infection during Pregnancy and Effects on Early Childhood Development, French Polynesia, 2013–2016

Lorenzo Subissi, Timothée Dub, Marianne Besnard, Teheipuaura Mariteragi-Helle, Tuxuan Nhan, Delphine Lutringer-Magnin, Philippe Barboza, Céline Gurry, Pauline Brindel, Eric J. Nilles, David Baud, Angela Merianos, Didier Musso, Judith R. Glynn, Gilles Dupuis, Van-Mai Cao-Lormeau1, Marine Giard1Comments to Author , and Henri-Pierre Mallet1
Author affiliations: World Health Organization, Geneva, Switzerland (L. Subissi, P. Barboza, C. Gurry, P. Brindel); Institut Pasteur, Paris, France (T. Dub); French Polynesia Hospital Center, Pirae, French Polynesia (M. Besnard, D. Lutringer-Magnin); Institut Louis Malardé, Papeete, French Polynesia (T. Mariteragi-Helle, T. Nhan, D. Musso, V.-M. Cao-Lormeau); Brigham and Women’s Hospital and Harvard Humanitarian Initiative, Boston, Massachusetts, USA (E.J. Nilles); World Health Organization, Manila, Philippines (E.J. Nilles, A. Merianos); University Hospital, Lausanne, Switzerland (D. Baud); Aix Marseille University, IRD, AP-HM, SSA, VITROME, IHU-Méditerranée Infection, Marseille, France (D. Musso); London School of Hygiene & Tropical Medicine, London, UK (J.R. Glynn); University of Québec, Montreal, Québec, Canada (G. Dupuis); Centre de Liaison sur l’Intervention et la Prévention Psychosociales, Montreal (G. Dupuis); Bureau de Veille Sanitaire, Direction de la Santé, Papeete (M. Giard, H.-P. Mallet)

Main Article

Table 1

Main and secondary diagnoses for 21 case-patients recruited in case-control study of Zika virus infection during pregnancy and effects on early childhood development, French Polynesia, 2013–2016

Diagnoses No. (%) Pregnancy termination Live births Child alive,* n = 7
Main diagnoses
Microcephaly 7 (33) 4 3 1
Brainstem dysfunction of the neonate 5 (24) 0 5 3
Other CNS congenital defects 9 (43) 6 3 3
Septal and/or corpus callosum agenesis 3 (14) 1 2 2
Intraventricular hemorrhage 1 (5) 0 1 1
Cerebral hemorrhage and placental calcifications 1 (5) 1 1 0
Polymalformative syndrome 2 (10) 2 0 0
Complete or sacral spina bifida
 2 (10)
 2
 0
 0
Secondary diagnoses
Ventriculomegaly 6 (29) 4 2 2
Arthrogryposis 3 (14) 3 0 0

*As of July 2017.

Main Article

1These authors contributed equally to this article.

Page created: September 16, 2018
Page updated: September 16, 2018
Page reviewed: September 16, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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