Volume 24, Number 11—November 2018
Synopsis
Epidemiology of Buruli Ulcer Infections, Victoria, Australia, 2011–2016
Michael J. Loftus, Ee Laine Tay, Maria Globan, Caroline J. Lavender, Simon R. Crouch, Paul D.R. Johnson1
, and Janet A.M. Fyfe1
, and Janet A.M. Fyfe1
Table 4
Demographic and clinical data and management strategies for Buruli ulcer case-patients, by resident status, Victoria, Australia, 2011–2016*
| Characteristic |
Residents | Nonresidents | Overall |
|||||
|---|---|---|---|---|---|---|---|---|
| All |
BP |
MP |
p value† |
All |
p value‡ |
|||
| Total no. cases |
369 |
146 |
151 |
221 |
600 |
|||
| Age, y | ||||||||
| Median (IQR) | 58 (38–71) | 55 (33–71) | 59 (40–71) | 0.7081 | 44 (24–65) | <0.0001 | 54 (31–9) | |
| <15 | 32 (8.7) | 11 (7.5) | 13 (8.6 | 39 (17.6) | 72 (12) | |||
| 15–60 | 168 (45.5) | 72 (49.3) | 65 (43) | 110 (49.8) | 285 (47.5) | |||
| >6 |
169 (45.8) |
63 (43.2) |
73 (48.3) |
0.555 |
72 (32.6) |
<0.0001 |
243 (40.5) |
|
| Sex | ||||||||
| M | 213 (57.7) | 79 (54.1) | 94 (62.3) | 124 (56.1) | 258 (43) | |||
| F |
156 (42.3) |
67 (45.9) |
57 (37.7) |
0.155 |
97 (43.9) |
0.701 |
342 (57) |
|
| Year of diagnosis, total no. | 369 | 146 | 151 | 221 | 600 | |||
| 2011 | 57 (15.4) | 43 (29.5) | 4 (2.6) | 23 (10.4) | 80 (13.3) | |||
| 2012 | 46 (12.5) | 34 (23.3) | 4 (2.6) | 29 (13.1) | 77 (12.8) | |||
| 2013 | 38 (10.3) | 16 (11) | 13 (8.6) | 25 (11.3) | 65 (10.8) | |||
| 2014 | 52 (14.1) | 24 (16.4) | 16 (10.6) | 34 (15.4) | 89 (14.8) | |||
| 2015 | 77 (20.9) | 18 (12.3) | 46 (30.5) | 29 (13.1) | 107 (17.8) | |||
| 2016 |
99 (26.8) |
11 (7.5) |
68 (45) |
<0.0001 |
81 (36.7) |
182 (30.3) |
||
| WHO category, total no. | 305 | 118 | 127 | 208 | 523 | |||
| I | 251 (82.3) | 102 (86.4) | 103 (81.1) | 156 (70.6) | 415 (79.3) | |||
| II | 35 (11.5) | 13 (11) | 15 (11.8) | 35 (15.8) | 71 (13.6) | |||
| III |
19 (6.2) |
3 (2.5) |
9 (7.1) |
0.338 |
17 (7.7) |
0.129 |
37 (7.1) |
|
| Median time to seeking healthcare, d (IQR) | 28 (14–60) | 21 (14–42) | 28 (14–60) | 0.1853 | 30 (14–60) | 0.5253 | 28 (14–60) | |
| Median time to diagnosis, d (IQR) |
48 (27–94) |
34 (22–62) |
51 (29–95) |
0.0016 |
79 (48–123) |
<0.0001 |
63 (35–109) |
|
| Treatment, total no. | 301 | 124 | 129 | 206 | 517 | |||
| Antimicrobial drugs only | 208 (69.1) | 90 (72.6) | 86 (66.7) | 115 (55.8) | 328 (63.4) | |||
| Surgery only | 17 (5.6) | 7 (5.6) | 5 (3.9) | 10 (4.9) | 27 (5.2) | |||
| Antimicrobial drugs and surgery |
76 (25.2) |
27 (21.8) |
28 (21.7) |
0.844 |
81 (39.3) |
0.003 |
162 (31.3) |
|
| Surgical treatment, total no. | 78 | 27 | 27 | 83 | 165 | |||
| Debridement | 27 (34.6) | 13 (48.1) | 10 (37) | 26 (31.3) | 54 (32.7) | |||
| Narrow excision | 26 (33.3) | 6 (22.2) | 10 (37) | 24 (28.9) | 53 (32.1) | |||
| Wide excision | 25 (32.1) | 8 (29.6) | 7 (25.9) | 0.482 | 33 (39.8) | 0.592 | 58 (35.2) | |
*Values are no. (%) patients except as indicated. BP, Bellarine Peninsula; IQR, interquartilie range; MP, Mornington Peninsula; WHO, World Health Organization.
†p value provides comparison between Bellarine Peninsula residents and Mornington Peninsula residents.
‡p value provides comparison between all residents and nonresidents.
1Joint senior authors.
Page created: October 16, 2018
Page updated: October 16, 2018
Page reviewed: October 16, 2018
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