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Volume 24, Number 11—November 2018
Synopsis

Epidemiology of Buruli Ulcer Infections, Victoria, Australia, 2011–2016

Michael J. Loftus, Ee Laine Tay, Maria Globan, Caroline J. Lavender, Simon R. Crouch, Paul D.R. Johnson1Comments to Author , and Janet A.M. Fyfe1
Author affiliations: Victorian Department of Health and Human Services, Melbourne, Victoria, Australia (M.J. Loftus, E.L. Tay, S.R. Crouch); Austin Health, Heidelberg, Victoria, Australia (M.J. Loftus, P.D.R. Johnson); Victorian Infectious Diseases Reference Laboratory, Melbourne (M. Globan, C.J. Lavender, J.A.M. Fyfe); The University of Melbourne, Parkville, Victoria, Australia (P.D.R. Johnson)

Main Article

Table 2

Clinical site and severity, delays to first healthcare visit and diagnosis, and management strategies for Buruli ulcer case-patients, by sex, Victoria, Australia, 2011–2016*

Variable
 Male
 Female
 p value†
Total no.
 342 (57.0)
 258 (43.0)
Lesion site, total no. 333 252 0.116‡
Lower limb 231 (69.4) 193 (76.6)
Below knee 167 (50.2) 139 (55.2)
Knee or above 39 (11.7) 47 (18.7)
Unspecified 25 (7.5) 7 (2.8)
Upper limb 87 (26.1) 53 (21)
Other sites 8 (2.4) 4 (1.6)
Head/neck 2 (0.6) 3 (1.2)
Torso 4 (1.2) 0 (0.0)
Buttock/perineum 2 (0.6) 1 (0.4)
>1 site
 8 (2.4)
 2 (0.8)
WHO category, total no. 295 228 0.078
I 226 (76.6) 189 (82.9)
II 42 (14.2) 29 (12.7)
III
 27 (9.2)
 10 (4.4)
Time to healthcare visit 0.6153
Median (IQR), d
 29 (14–60)
 28(14–42)
Time to diagnosis 0.5134
Median (IQR), d
 63 (35–109)
 65(36–117)
All treatment, total no. 296 221 0.03
Antimicrobial drugs only 189 (63.9) 139 (62.9)
Surgery only 9 (3.0) 18 (8.1)
Antimicrobial drugs and surgery
 98 (33.1)
 64 (29)
Surgical treatment, total no. 91 74 0.331
Debridement 33 (36.3) 21 (28.4)
Narrow excision 25 (27.5) 28 (37.8)
Wide excision 33 (36.3) 25 (33.8)

*Values are no. (%) patients except as indicated. IQR, interquartile range; WHO, World Health Organization.
†p value provides comparisons across all categories.
‡p value provides comparison between lower limb, upper limb, all other sites, and patient sex.

Main Article

1Joint senior authors.

Page created: October 16, 2018
Page updated: October 16, 2018
Page reviewed: October 16, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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