Volume 24, Number 12—December 2018
Dispatch
In-Host Adaptation of Salmonella enterica Serotype Dublin during Prosthetic Hip Joint Infection
Figure

Figure. Genomic and phenotypic characteristics of Salmonella enterica serotype Dublin isolates Str.2011, Str.2014, and Str.2015 from a 74-year-old woman who had recurrent infections involving hip joint prostheses, France. A) Tree constructed after mapping the sequences of the isolates to reference genomes of Salmonella Dublin strains CT_020221853 and 3246 (GenBank accession nos. CP001144.1 and CM001151.1, respectively). The 4 nonsynonymous SNPs and the corresponding coding genes are shown. Scale bar indicates genetic distance. B) Genes in Str.2011 and altered in Str.2014 and Str.2015 (reference strain Salmonella Dublin CT_02021853) are indicated by black and white boxes, respectively. Positive phenotypic tests are indicated as black boxes. For carbohydrate metabolism, only carbohydrates used by Str.2011 and not used by Str.2014 and/or Str.2015 are shown. *Gene ID annotation based on reference strain Salmonella Dublin str. CT_02021853 (GenBank accession no. CP001144.1). Genetic events found: †14-bp deletion; ‡16-bp insertion; §790-bp deletion (total gene deletion). SNP, single-nucleotide polymorphism.