Volume 24, Number 12—December 2018
Research
CTX-M-65 Extended-Spectrum β-Lactamase–Producing Salmonella enterica Serotype Infantis, United States1
, Jessica C. Chen, Louise K. Francois Watkins, Davina Campbell, Jason P. Folster, Heather Tate, Jamie Wasilenko, Christine Van Tubbergen, and Cindy R. Friedman
Table 1
Characteristics of patients and 30 Salmonella enterica serotype Infantis pattern JFXX01.0787 isolates associated with CTX-M-65, United States*
| Accession no.† | Year | Specimen source | Resistance profile | Plasmids | gyrA | parC | Hospitalized | Recent travel | Prolonged infection‡ |
|---|---|---|---|---|---|---|---|---|---|
| SRR2485281 |
2012 |
Urine |
ACSuTCxTioCip(I)NalCot
Gen(I) |
IncFIB-like |
D87Y |
Wt |
Yes |
Peru |
|
| SRR2485278 |
2012 |
Blood |
ACSuTCxTioFoxCip(I)NalCotGen(I) |
IncFIB-like |
D87Y |
Wt |
No data |
Peru |
Yes |
| SRR4019593 |
2013 |
Feces |
ASuTCxTioCip(I)NalCotGen |
IncFIB-like |
D87Y |
Wt |
No data |
No data |
|
| SRR4019592 |
2013 |
Feces |
ACSuTCxTioCip(I)NalCotGen |
IncFIB-like |
D87Y |
Wt |
No data |
No data |
|
| SRR2485284 |
2013 |
Feces |
ACSuTCxTioCip(I)NalCot
Gen(I) |
IncFIB-like |
D87Y |
Wt |
No data |
No data |
Yes |
| SRR4025935 |
2013 |
Feces |
ACSuTCxTioCip(I)Nal |
IncFIB-like |
D87Y |
Wt |
No |
Peru |
|
| SRR4025936 |
2013 |
Feces |
ACSuTCxTioCip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
No data |
Peru |
Yes |
| SRR3178069 |
2013 |
Feces |
ACSuTCxTioCip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
No |
Peru |
Yes |
| SRR4019589 |
2014 |
Feces |
ACSSuTCxTioCip(I)NalCot
Gen |
IncFIB-like |
D87Y |
Wt |
No |
Ecuador |
|
| SRR2407791 |
2014 |
Retail chicken meat |
ACTCxTioCip(I)NalGen(I) |
IncFIB-like |
D87Y |
Wt |
NA |
NA |
NA |
| SRR2353201 |
2014 |
Feces |
ACSSuTCxTioCip(I)NalCot
Gen(I) |
IncFIB-like |
D87Y |
Wt |
No data |
No data |
|
| SRR4025938 |
2014 |
Feces |
ACSuTCxTioCip(I)NalCot
Gen(I) |
IncFIB-like |
D87Y |
Wt |
No data |
No data |
|
| SRR2485287 |
2014 |
Feces |
ACSSuTAug(I)CxTioFox
Cip(I)NalCotGen(I) |
IncFIB-like |
D87Y |
Wt |
No data |
No data |
Yes |
| SRR4019601 |
2014 |
Feces |
ASSuTCxTioCip(I)NalCotGen |
IncFIB-like |
D87Y |
Wt |
No data |
No data |
Yes |
| SRR4019595 |
2014 |
Feces |
ACSSuTCxTioCip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
No |
No travel |
|
| SRR2485288 |
2014 |
Feces |
ACSSuTCxTioCip(I)NalCot
Gen(I) |
IncFIB-like |
D87Y |
Wt |
No data |
No travel |
|
| SRR2485282 |
2014 |
Feces |
ACSSuTCxTioCip(I)NalCot
Gen(I) |
IncFIB-like |
D87Y |
Wt |
No |
Peru |
Yes |
| SRR2485286 |
2014 |
Feces |
ASSuTCxTioCip(I)NalCotGen |
IncFIB-like |
D87Y |
Wt |
Yes |
Peru |
|
| SRR3178071 |
2014 |
Feces |
ACSSuTCxTioCip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
Yes |
Peru |
|
| SRR4019602 |
2015 |
Feces |
ACSSuTCxTioFox(I)Cip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
No |
Ecuador |
|
| SRR4019594 |
2015 |
Feces |
ACSSuTCxTioCip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
No data |
No data |
|
| SRR3185043 |
2015 |
Urine |
ACSSuTCxTioCip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
No |
No data |
Yes |
| SRR4019591 |
2015 |
Feces; urine |
ACSSuTCxTioCip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
Yes |
No data |
Yes |
| SRR4019588 |
2015 |
Feces |
ACSuTCxTioCip(I)NalCot
Gen(I) |
IncFIB-like, colE |
D87Y |
Wt |
Yes |
No travel |
Yes |
| SRR4019587 |
2015 |
Feces |
ACSSuTCxTioCip(I)Nal
Gen(I) |
IncFIB-like |
D87Y |
Wt |
No |
No travel |
|
| SRR3184311 |
2015 |
Feces |
ACSSuTCxTioCip(I)NalCot
Gen(I) |
IncFIB-like |
D87Y |
Wt |
Yes |
No travel |
Yes |
| SRR4019590 |
2015 |
Feces |
ACSuTCxTioCip(I)NalCot |
pXuzhou21, IncFIB-like |
D87Y |
Wt |
Yes |
No travel |
|
| SRR4019603 |
2015 |
Urine |
ACSSuTCxTioCip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
No |
No travel |
|
| SRR3178070 |
2015 |
Urine |
ACSSuTCxTioCip(I)NalCot |
IncFIB-like |
D87Y |
Wt |
Yes |
Peru |
|
| SRR4019600 | 2015 | Feces | ACSuTCxTioCip(I)NalCot | IncFIB-like | D87Y | Wt | No | Peru | Yes |
*A, ampicillin; Aug, amoxicillin-clavulanic acid; C, chloramphenicol; Cip, ciprofloxacin; Cot, trimethoprim/sulfamethoxazole; Cx, ceftriaxone; Cx, ceftriaxone; Fox, cefoxitin; Gen, gentamicin; (I), intermediate susceptibility; NA, not applicable; Nal, nalidixic acid; S, streptomycin; Su, sulfisoxazole; T, tetracycline; Tio, ceftiofur.
†Accession numbers are the sequence read archive run identification numbers from the National Center for Biotechnology Information.
‡Documented illness >2 wk after symptom onset. Blank cells indicate no evidence of prolonged infection (either no additional data were available or additional data indicated no clear evidence of prolonged infection).
1Preliminary results from this analysis were presented at the International Salmonella and Salmonellosis Symposium, June 6–8, 2016, St. Malo, France, and at the International Association for Food Protection Annual Meeting, July 9–12, 2017, Tampa, Florida, USA.