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Volume 24, Number 12—December 2018
Research

CTX-M-65 Extended-Spectrum β-Lactamase–Producing Salmonella enterica Serotype Infantis, United States1

Allison C. BrownComments to Author , Jessica C. Chen, Louise K. Francois Watkins, Davina Campbell, Jason P. Folster, Heather Tate, Jamie Wasilenko, Christine Van Tubbergen, and Cindy R. Friedman
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A.C. Brown, J.C. Chen, L.K. Francois Watkins, D. Campbell, J.P. Folster, C. Van Tubbergen, C.R. Friedman); Food and Drug Administration, Laurel, Maryland, USA (H. Tate); US Department of Agriculture, Athens, Georgia, USA (J. Wasilenko)

Main Article

Table 1

Characteristics of patients and 30 Salmonella enterica serotype Infantis pattern JFXX01.0787 isolates associated with CTX-M-65, United States*

Accession no.† Year Specimen source Resistance profile Plasmids gyrA parC Hospitalized Recent travel Prolonged infection‡
SRR2485281
2012
Urine
ACSuTCxTioCip(I)NalCot
Gen(I)
IncFIB-like
D87Y
Wt
Yes
Peru

SRR2485278
2012
Blood
ACSuTCxTioFoxCip(I)NalCotGen(I)
IncFIB-like
D87Y
Wt
No data
Peru
Yes
SRR4019593
2013
Feces
ASuTCxTioCip(I)NalCotGen
IncFIB-like
D87Y
Wt
No data
No data

SRR4019592
2013
Feces
ACSuTCxTioCip(I)NalCotGen
IncFIB-like
D87Y
Wt
No data
No data

SRR2485284
2013
Feces
ACSuTCxTioCip(I)NalCot
Gen(I)
IncFIB-like
D87Y
Wt
No data
No data
Yes
SRR4025935
2013
Feces
ACSuTCxTioCip(I)Nal
IncFIB-like
D87Y
Wt
No
Peru

SRR4025936
2013
Feces
ACSuTCxTioCip(I)NalCot
IncFIB-like
D87Y
Wt
No data
Peru
Yes
SRR3178069
2013
Feces
ACSuTCxTioCip(I)NalCot
IncFIB-like
D87Y
Wt
No
Peru
Yes
SRR4019589
2014
Feces
ACSSuTCxTioCip(I)NalCot
Gen
IncFIB-like
D87Y
Wt
No
Ecuador

SRR2407791
2014
Retail chicken meat
ACTCxTioCip(I)NalGen(I)
IncFIB-like
D87Y
Wt
NA
NA
NA
SRR2353201
2014
Feces
ACSSuTCxTioCip(I)NalCot
Gen(I)
IncFIB-like
D87Y
Wt
No data
No data

SRR4025938
2014
Feces
ACSuTCxTioCip(I)NalCot
Gen(I)
IncFIB-like
D87Y
Wt
No data
No data

SRR2485287
2014
Feces
ACSSuTAug(I)CxTioFox
Cip(I)NalCotGen(I)
IncFIB-like
D87Y
Wt
No data
No data
Yes
SRR4019601
2014
Feces
ASSuTCxTioCip(I)NalCotGen
IncFIB-like
D87Y
Wt
No data
No data
Yes
SRR4019595
2014
Feces
ACSSuTCxTioCip(I)NalCot
IncFIB-like
D87Y
Wt
No
No travel

SRR2485288
2014
Feces
ACSSuTCxTioCip(I)NalCot
Gen(I)
IncFIB-like
D87Y
Wt
No data
No travel

SRR2485282
2014
Feces
ACSSuTCxTioCip(I)NalCot
Gen(I)
IncFIB-like
D87Y
Wt
No
Peru
Yes
SRR2485286
2014
Feces
ASSuTCxTioCip(I)NalCotGen
IncFIB-like
D87Y
Wt
Yes
Peru

SRR3178071
2014
Feces
ACSSuTCxTioCip(I)NalCot
IncFIB-like
D87Y
Wt
Yes
Peru

SRR4019602
2015
Feces
ACSSuTCxTioFox(I)Cip(I)NalCot
IncFIB-like
D87Y
Wt
No
Ecuador

SRR4019594
2015
Feces
ACSSuTCxTioCip(I)NalCot
IncFIB-like
D87Y
Wt
No data
No data

SRR3185043
2015
Urine
ACSSuTCxTioCip(I)NalCot
IncFIB-like
D87Y
Wt
No
No data
Yes
SRR4019591
2015
Feces; urine
ACSSuTCxTioCip(I)NalCot
IncFIB-like
D87Y
Wt
Yes
No data
Yes
SRR4019588
2015
Feces
ACSuTCxTioCip(I)NalCot
Gen(I)
IncFIB-like, colE
D87Y
Wt
Yes
No travel
Yes
SRR4019587
2015
Feces
ACSSuTCxTioCip(I)Nal
Gen(I)
IncFIB-like
D87Y
Wt
No
No travel

SRR3184311
2015
Feces
ACSSuTCxTioCip(I)NalCot
Gen(I)
IncFIB-like
D87Y
Wt
Yes
No travel
Yes
SRR4019590
2015
Feces
ACSuTCxTioCip(I)NalCot
pXuzhou21, IncFIB-like
D87Y
Wt
Yes
No travel

SRR4019603
2015
Urine
ACSSuTCxTioCip(I)NalCot
IncFIB-like
D87Y
Wt
No
No travel

SRR3178070
2015
Urine
ACSSuTCxTioCip(I)NalCot
IncFIB-like
D87Y
Wt
Yes
Peru

SRR4019600 2015 Feces ACSuTCxTioCip(I)NalCot IncFIB-like D87Y Wt No Peru Yes

*A, ampicillin; Aug, amoxicillin-clavulanic acid; C, chloramphenicol; Cip, ciprofloxacin; Cot, trimethoprim/sulfamethoxazole; Cx, ceftriaxone; Cx, ceftriaxone; Fox, cefoxitin; Gen, gentamicin; (I), intermediate susceptibility; NA, not applicable; Nal, nalidixic acid; S, streptomycin; Su, sulfisoxazole; T, tetracycline; Tio, ceftiofur.
†Accession numbers are the sequence read archive run identification numbers from the National Center for Biotechnology Information.
‡Documented illness >2 wk after symptom onset. Blank cells indicate no evidence of prolonged infection (either no additional data were available or additional data indicated no clear evidence of prolonged infection).

Main Article

1Preliminary results from this analysis were presented at the International Salmonella and Salmonellosis Symposium, June 6–8, 2016, St. Malo, France, and at the International Association for Food Protection Annual Meeting, July 9–12, 2017, Tampa, Florida, USA.

Page created: November 20, 2018
Page updated: November 20, 2018
Page reviewed: November 20, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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