Volume 24, Number 2—February 2018
Research
Borrelia miyamotoi Infections in Humans and Ticks, Northeastern China
Table
Epidemiologic, clinical, and laboratory testing features of 14 patients with Borrelia miyamotoi infections, northeastern China, May 2013–June 2015*
Characteristic |
Patient no. | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
13 |
14 |
|
Epidemiologic features | ||||||||||||||
Sex | F | M | F | M | M | M | M | M | M | F | M | M | M | M |
Age, y | 46 | 30 | 31 | 47 | 41 | 43 | 49 | 52 | 10 | 65 | 36 | 48 | 52 | 43 |
History of tick bite | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
Place of exposure to ticks | Forest | Forest | Forest | Forest | Forest | Forest | Forest | Forest | Home | Forest | Forest | Forest | Forest | Forest |
Tick bite location | Arm | Trunk | Neck | Ear | Leg | Trunk | Trunk | Trunk | Scalp | Arm | Trunk | Trunk | Trunk | Trunk |
Days from tick
exposure to
illness onset |
18 |
28 |
16 |
5 |
3 |
7 |
7 |
25 |
4 |
10 |
26 |
6 |
4 |
40 |
Clinical manifestations | ||||||||||||||
Fever, °C | 38.4 | 39.7 | 39 | 39 | – | – | 39.6 | 38.5 | – | – | – | – | – | – |
Asthenia | + | + | + | + | – | – | – | – | + | – | – | – | – | – |
Headache | + | + | + | + | – | – | – | + | – | – | – | + | – | – |
Anorexia | + | – | + | + | – | – | – | + | – | – | – | + | – | – |
Myalgia | – | – | – | – | – | – | + | – | – | – | – | – | – | – |
Arthralgia | – | + | + | – | – | – | + | – | – | – | – | – | – | – |
Lymphadenopathy | – | – | – | – | – | – | – | – | + | – | – | – | – | – |
Rash | – | – | – | – | – | – | – | – | – | + | – | – | – | – |
Eschar |
– |
– |
– |
– |
– |
– |
– |
– |
+ |
– |
– |
– |
– |
– |
Laboratory findings† | ||||||||||||||
Leukocytes, 109/L | 7.9 | 9.6 | 8.9 | 11.7 | 5.1 | NA | 4.3 | NA | 9.9 | 7.6 | NA | 6.3 | 5.4 | 11.8 |
Lymphocytes, 109 cells/L | 0.9 | 0.6 | 0.9 | 1.8 | 1.7 | NA | 0.3 | NA | 3 | 2.2 | NA | 2 | 2.5 | 1.2 |
Neutrophils, 109 cells/L | 7.4 | 5.5 | 8.4 | 8.3 | 2.7 | NA | 3.9 | NA | 6 | 16.9 | NA | 4.2 | 2.7 | 9.7 |
Platelets, 109/L | 164 | 130 | 173 | 210 | 218 | NA | 79 | NA | 298 | 200 | NA | 172 | 137 | 269 |
AST, U/L | 94.4 | 30.5 | 13.9 | 31 | 16.7 | NA | 60 | NA | 11.4 | NA | NA | 22 | 10.7 | NA |
ALT, U/L | 124.6 | 17.8 | 12.1 | 26.1 | 24.3 | NA | 71.6 | NA | 8 | NA | NA | 39.5 | 16.2 | NA |
Hospital stay (d) | Yes (17) | Yes (3) | Yes (15) | Yes (20) | No | No | No | No | No | No | No | No | No | No |
Co-infection | No | No | No | CRT | CRT | AC | No | No | No | No | No | No | No | No |
*AC, Anaplasma capra; ALT, alanine aminotransferase; AST: aspartate aminotransferase; CRT, Candidatus Rickettsia tarasevichiae; NA, not applicable; +, positive; –, negative.
†Normal ranges: leukocyte count, 4–10 × 109 cells/L; lymphocyte count, 0.8–4 × 109 cells/L; neutrophil count, 2–7 × 109 cells/L; platelet count, 100–300 × 109/L; AST, 8–40 U/L; ALT, 5–40 U/L.
1These authors contributed equally to this article.