Table 3

Characteristics Associated with Negative Interferon-γ Release Assay Results in Culture-Confirmed Tuberculosis Patients, Texas, USA, 2013–2015

Duc T. Nguyen, Larry D. Teeter, Julie Graves, and Edward A. Graviss

Author affiliations: Houston Methodist Research Institute, Houston, Texas, USA (D.T. Nguyen, E.A. Graviss); Forensic Research and Analysis, Portland, Oregon, USA (L.D. Teeter); University of Medicine and Health Sciences, New York, New York, USA (J. Graves); University of Texas School of Public Health, Houston (J. Graves)

Main Article

Multivariate analysis of association between negative IGRA results and culture-confirmed TB patient characteristics, by IGRA type, Texas, USA, 2013–2015*

Variable	All IGRA results, N = 1,338†		QFT only, n = 875†		T-SPOT.TB only, n = 463†
Variable	aOR (95% CI)	p value	aOR (95% CI)	p value	aOR (95% CI)	p value
Age in years	1.02 (1.01–1.03)	<0.001	1.02 (1.01–1.04)	<0.001	1.02 (1.00–1.03)	0.01
Non-Hispanic white race/ethnicity	2.61 (1.70–4.02)	<0.001	2.76 (1.60–4.76)	<0.001	2.29 (1.11–4.73)	0.03
HIV-positive status	2.72 (1.56–4.77)	<0.001	3.59 (1.86–6.94)	<0.001	1.34 (0.44–4.07)	0.60
Tested by T-SPOT.TB	1.58 (1.12–2.24)	0.01	–	–	–	–
Time from diagnosis to treatment	1.00 (1.00–1.01)	0.046	1.00 (1.00–1.01)	0.22	1.01 (1–1.01)	0.03

*aOR, adjusted odds ratio; IGRA, interferon-γ release assay; QFT, QuantiFERON-TB Gold In-Tube; TB, tuberculosis; –, analysis could not be performed.
†Multiple logistic models were run by using data from patients having complete data sets for all the included variables; aORs were from the multiple logistic regression models.

Main Article

Page created: February 15, 2018

Page updated: February 15, 2018

Page reviewed: February 15, 2018

The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.