Chronic Genotype 3 Hepatitis E in Pregnant Woman Receiving Infliximab and Azathioprine
Caroline Charre
, Christophe Ramière, Jérôme Dumortier, Florence Abravanel, Sébastien Lhomme, Rodica Gincul, and Caroline Scholtès
Author affiliations: Hospices Civils de Lyon, Lyon, France (C. Charre, C. Ramière, J. Dumortier, R. Gincul, C. Scholtès); Claude Bernard University Lyon 1, Villeurbanne, France (C. Charre, C. Ramière, J. Dumortier, C. Scholtès); INSERM, Lyon (C. Charre, C. Ramière, C. Scholtès); INSERM, Toulouse, France (F. Abravanel, S. Lhomme); Centre Hospitalier Universitaire de Purpan, Toulouse (F. Abravanel, S. Lhomme); Université Paul Sabatier, Toulouse (F. Abravanel, S. Lhomme)
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Figure
Figure. Time courses of HEV viral load (A) and infliximab and azathioprine treatment (B) in pregnant woman with chronic hepatitis E who was undergoing immunosuppressive treatment for ulcerative colitis. HEV RNA levels, IgM and IgG positivity, and serum ALT levels are shown. Serum ALT is expressed as a multiple of ULN. Arrows indicate suspected and confirmed infection and delivery dates. Infliximab treatment occurred every 8 weeks. ALT, alanine aminotransferase; HEV, hepatitis E virus; ULN, upper limit of normal.
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