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Volume 24, Number 6—June 2018
Research

Influenza D Virus Infection in Feral Swine Populations, United States

Lucas Ferguson1, Kaijian Luo1, Alicia K. Olivier, Fred L. CunninghamComments to Author , Sherry Blackmon, Katie Hanson-Dorr, Hailiang Sun2, John Baroch, Mark W. Lutman, Bianca Quade, William Epperson, Richard Webby, Thomas J. DeLiberto, and Xiu-Feng WanComments to Author 
Author affiliations: Mississippi State University, Starkville, Mississippi, USA (L. Ferguson, K. Luo, A.K. Olivier, S. Blackmon, H. Sun, B. Quade, W. Epperson, X.-F. Wan); South China Agricultural University, Guangzhou, China (K. Luo); US Department of Agriculture, Starkville (F.L. Cunningham, K. Hanson-Dorr); US Department of Agriculture, Fort Collins, Colorado, USA (J. Baroch, M.W. Lutman, T.J. DeLiberto); St. Jude Children’s Research Hospital, Memphis, Tennessee, USA (R. Webby)

Main Article

Table 3

Summary of viral shedding and seroconversion in evaluation of characteristics of influenza D virus infection in feral swine*

Timeline
 HAI titer
 Nasal titer
Inoculated swine, dpi, n = 12
3 0 (12) 7 (12)
5 6 (11) 6 (11)
7 8 (8) 0 (8)
9 5 (5) 0 (5)
11 3 (3) 0 (3)
21
 1 (1)
 0 (1)
Control swine, dpi, n = 6‡
3 0 (6) 0 (6)
5 0 (5) 0 (5)
7 0 (3) 0 (3)
9 0 (2) 0 (2)
11 0 (1) 0 (1)
21
 0 (1)
 0 (1)
Contact swine, dpe, n = 8§
1 0 (8) 0 (8)
3 0 (7) 0 (7)
5 0 (6) 1 (6)
7 0 (5) 1 (5)
9 0 (4) 1 (4)
19 1 (3) 0 (3)

*HAI titer data indicate number of swine that seroconverted (no. tested). Seropositivity defined as HAI titer >1:40. Nasal titer data indicate number of swine that shed virus (no. tested). Animals with a nasal wash viral titer >0.699 log10 TCID50/mL were considered as shedding virus. dpe, days postexposure; dpi, days postinoculation; HAI, hemagglutination inhibition; TCID50, 50% tissue culture infective dose.
†Feral swine inoculated with influenza D/bovine/C00046N/Mississippi/2014 virus.
‡Feral swine inoculated with sterile phosphate-buffered saline.
§Feral swine with direct-contact exposure to influenza D virus–inoculated swine.

Main Article

1These authors contributed equally to this article.

2Current affiliation: South China Agricultural University, Guangzhou, China.

Page created: May 17, 2018
Page updated: May 17, 2018
Page reviewed: May 17, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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