Volume 24, Number 7—July 2018
Synopsis
Typhus Group Rickettsiosis, Germany, 2010–20171
Jessica Rauch, Philip Eisermann, Bernd Noack, Ute Mehlhoop, Birgit Muntau, Johannes Schäfer, and Dennis Tappe
Table 1
Characteristics of 28 patients with typhus group rickettsiosis, Germany, 2010–2017*
| Patient no. | Age, y/sex | Year of diagnosis | Travel history | PCR result† | Signs and symptoms | Hospitalized |
|---|---|---|---|---|---|---|
| 1 | 26/M | 2016 | Indonesia (Java), Singapore | Negative | Fever, exanthema, femoral lymphadenitis | Yes |
| 2 | 4/M | 2016 | The Gambia | Negative | Fever, myalgia, pneumonia | Yes |
| 3 | 27/M | 2015 | Indonesia (Java, Bali, Gili, Lombok) | NA | Fever, headache | Yes |
| 4 | 27/M | 2015 | Indonesia (Lombok, Komodo, Flores, Gili, Bali, Java) | NA | Fever, headache, exanthema | Yes |
| 5 | 76/F | 2015 | Canary Islands | NA | Fever, exanthema, dysuria | Yes |
| 6 | 21/F | 2015 | Thailand | NA | Fever, exanthema, genital herpes | No |
| 7 | 27/F | 2015 | Cameroon | Negative | Fever, headache, acute kidney injury | Yes |
| 8 | 26/F | 2015 | NA | NA | NA | NA |
| 9 | 80/F | 2015 | No (Germany) | NA | Fever, headache, arthralgia, myalgia | No |
| 10 | 42/M | 2014 | Thailand | Negative | Fever, exanthema | Yes |
| 11 | 25/F | 2014 | Florida | NA | Cough, reddened ear | No |
| 12 | 31/F | 2014 | Indonesia (Bali) | Negative | Fever, headache, exanthema | No |
| 13 | 28/M | 2014 | Greece | R. typhi‡ | Fever, fatigue | Yes |
| 14 | 31/M | 2014 | Indonesia (Bali) | NA | Fever, exanthema | Yes |
| 15 | 72/M | 2014 | No (Germany) | NA | Pneumonia, pleural effusion | Yes |
| 16 | 34/F | 2014 | Costa Rica | NA | Headache | No |
| 17 | 57/M | 2013 | Cambodia | R. typhi§ | Fever, headache, exanthema, splenomegaly | Yes |
| 18 | 75/M | 2013 | Texas | Negative | Exanthema, confusion, hallucination, fatigue | Yes |
| 19 | 58/M | 2013 | Greece | NA | Fever, exanthema, arthralgia, fatigue | Yes |
| 20 | 28/F | 2013 | Indonesia (Bali, Gili) | Negative | Fever, headache, myalgia, splenomegaly, fatigue | Yes |
| 21 | 50/F | 2012 | No (Germany) | NA | Arthralgia | No |
| 22 | 23/M | 2012 | Burkina Faso | Negative | Fever, diarrhea | Yes |
| 23 | 21/M | 2012 | Namibia | NA | Fever, exanthema | No |
| 24 | 53/M | 2012 | Cambodia | Negative | Fever, headache, exanthema, arthralgia | No |
| 25 | 26/M | 2011 | Cambodia | NA | Fever, headache, exanthema | Yes |
| 26 | 47/M | 2011 | Indonesia (Java, Bali) | Negative | Fever, headache, arthralgia, splenomegaly | No |
| 27 | 22/M | 2011 | Indonesia (Bali, Lombok) | Negative | Fever, headache, arthralgia | Yes |
| 28 | 34/F | 2010 | Nepal | R. typhi§ | Fever, headache, exanthema, pneumonia | Yes |
*NA, not available.
†Rickettsia typhi–specific and R. prowazekii–specific nested prsA quantitative PCR.
‡Nested R. typhi–specific prsA quantitative PCR from liver biopsy sample, positive; from serum sample, negative.
§Also positive ompB PCR from whole blood.
1Part of this study was orally presented at the annual meeting of the German Society for Hygiene and Microbiology, February 19–21, 2018, Bochum, Germany.
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