Volume 24, Number 7—July 2018
Dispatch
Guiana Dolphin Unusual Mortality Event and Link to Cetacean Morbillivirus, Brazil
Kátia R. Groch
, Elitieri B. Santos-Neto, Josué Díaz-Delgado, Joana M.P. Ikeda, Rafael R. Carvalho, Raissa B. Oliveira, Emi B. Guari, Tatiana L. Bisi, Alexandre F. Azevedo, José Lailson-Brito, and José L. Catão-Dias
, Elitieri B. Santos-Neto, Josué Díaz-Delgado, Joana M.P. Ikeda, Rafael R. Carvalho, Raissa B. Oliveira, Emi B. Guari, Tatiana L. Bisi, Alexandre F. Azevedo, José Lailson-Brito, and José L. Catão-Dias
Table 2
Summary of histopathologic findings for 6 Guiana dolphins recovered from Ilha Grande Bay, Rio de Janeiro, Brazil, 2017*
| No. | Tissue | Histopathologic findings |
|---|---|---|
| 1† | Lung | Marked, multifocal chronic bronchointerstitial pneumonia and proliferative pleuritis with sclerosis, type II pneumocyte hyperplasia, syncytia/multinucleated cells, rare INCIBs, calcified nematode debris and edema; multifocal tunica media hypertrophy/hyperplasia |
| Mammary gland | Mild to moderate, multifocal, chronic lymphoplasmacytic and histiocytic mastitis with acinar ectasia, inspissated secretion, scattered necrosis, ceroid pigment and moderate INCIBs in epithelium | |
| Heart | Mild, focal, subacute fibrinous pericarditis; mild, multifocal myocardial fibrosis | |
| Kidney | Mild, multifocal, chronic membranous glomerulonephritis with glomerulocysts, tubular proteinosis, protein casts, and scattered tubuloepithelial necrosis | |
| Pulmonary lymph node | Mild, multifocal, chronic nodular eosinophilic and necrotizing lymphadenitis with fibrosis and hemosiderosis; diffuse lymphoid depletion | |
| Mediastinal lymph node | Mild, multifocal, chronic eosinophilic lymphadenitis; diffuse congestion | |
| Spleen | Diffuse congestion and multifocal, acute capsular hemorrhage; extramedullary hematopoiesis | |
| Adrenal | Mild, multifocal, acute corticomedullary hemorrhage | |
| Aorta | Mild, segmental, chronic proliferative endarteritis | |
| Liver | Moderate, multifocal, chronic bile duct adenomatous hyperplasia | |
| Uterus | Moderate, multifocal, chronic arteriosclerosis and arterial elastosis | |
| Glandular stomach |
Mild, diffuse mucosal hyperplasia; multifocal arterial tunica media hypertrophy/hyperplasia |
|
| 2‡ | Lung | Mild, multifocal, acute interstitial pneumonia associated with marked alveolar edema, hemorrhage and alveolar histiocytosis, syncytia/multinucleated cells and keratin spicules |
| Kidney | Mild, multifocal, acute tubular degeneration and necrosis; mild, multifocal, acute tubular proteinosis and protein casts; marked, focal, acute perirenal hemorrhage | |
| Pulmonary lymph node | Moderate, diffuse cortical and paracortical lymphoid depletion with scattered lymphocytolysis | |
| Prescapular lymph node | Diffuse congestion with focal acute hemorrhage and erythrophagocytosis; sinus vascularization | |
| Spleen | Moderate, diffuse, lymphoid depletion with sinus histiocytosis; extramedullary hematopoiesis | |
| Heart | Moderate, multifocal, acute subendocardial and epicardial hemorrhage | |
| Adrenal | Marked, multifocal, acute cortico-medullary hemorrhagic necrosis | |
| Esophagus | Focal acute hemorrhage in serosa | |
| Urinary bladder | Edema and focal acute hemorrhage in serosa | |
| Penis | Urethral luminal hemorrhage with single cell epithelial necrosis/apoptosis | |
| Cerebrum, cerebellum |
Diffuse leptomeningeal congestion and perivascular edema in neuroparenchyma |
|
| 10§ | Lung | Mild to moderate, multifocal, chronic suppurative bronchopneumonia with adult nematodes (Halocercus sp.); multifocal alveolar, bronchiolar and bronchial mineralization |
| Keratinized stomach | Mild, focal, chronic proliferative gastritis | |
| Skeletal muscle |
Scattered acute hyaline myocyte degeneration and necrosis |
|
| 11 | Ascending aorta | Marked, segmental, chronic fibrosing and proliferative endarteritis with chondroid metaplasia and calcification; moderate, focal, chronic granulomatous periarteritis; mild, multifocal intimal fibroelastosis |
| Aortic (semilunar) valve |
Mild, multifocal, chronic intimal/endocardial fibroelastosis |
|
| 12¶ |
Keratinized stomach |
Mild, focal, chronic mononuclear gastritis |
| 13# | Lung | Marked, multifocal, chronic suppurative to pyogranulomatous bronchopneumonia with bronchial/olar sclerosis, adult and larval nematodes (Halocercus sp.) and moderate, multifocal, chronic proliferative and fibrosing (villous) pleuritis; marked, multifocal, chronic tunica media arterial hypertrophy/hyperplasia with stenosis |
| Skin | Mild, multifocal, chronic irregular epidermal hyperplasia | |
| Pyloric stomach | Moderate, focal, chronic granulomatous gastritis with numerous trematode ova (compatible with Pholeter gastrophilus) |
*INCIBs, intranuclear and intracytoplasmic inclusion bodies; no., animal no.
†No significant lesions were observed for large intestine, thyroid, skin, trachea, cerebrum, cerebellum, spinal cord, or skeletal muscle.
‡No significant lesions were observed for keratinized and pyloric stomach, tongue, aorta, small intestine, pancreas, or trachea.
§Unable to observe lesions in liver, spleen, kidney, testicle, trachea, small and large intestine, skin, periaortic lymph node, cerebrum, or cerebellum because of advanced autolysis of animal.
¶Unable to observe lesions in ovary, skin, liver, skeletal muscle, heart, kidney, spleen, large intestine, bladder, lymph node, or adrenal gland because of advanced autolysis of animal.
#Unable to observe lesions in small intestine, liver, skeletal muscle, adrenal gland, bladder, kidney, or heart because of advanced autolysis of animal.
Page created: June 18, 2018
Page updated: June 18, 2018
Page reviewed: June 18, 2018
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