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Volume 24, Number 9—September 2018
Dispatch

Zika Virus Seropositivity in 1–4-Year-Old Children, Indonesia, 2014

R. Tedjo SasmonoComments to Author , Rama Dhenni, Benediktus Yohan, Paul Pronyk, Sri Rezeki Hadinegoro, Elizabeth Jane Soepardi, Chairin Nisa Ma’roef, Hindra I. Satari, Heather Menzies, William A. Hawley, Ann M. Powers, Ronald Rosenberg, Khin Saw Aye Myint, and Amin Soebandrio
Author affiliations: Eijkman Institute for Molecular Biology, Jakarta, Indonesia (R.T. Sasmono, R. Dhenni, B. Yohan, C.N. Ma’roef, K.S.A. Myint, A. Soebandrio); UNICEF Indonesia, Jakarta (P. Pronyk); University of Witwatersrand School of Public Health, Johannesburg, South Africa (P. Pronyk); Universitas Indonesia Medical School, Jakarta (S.R. Hadinegoro, H.I. Satari); Cipto Mangunkusumo Hospital, Jakarta (S.R. Hadinegoro, H.I. Satari); Ministry of Health of the Republic of Indonesia, Jakarta (E.J. Soepardi); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (H. Menzies, W.A. Hawley); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (A.M. Powers, R. Rosenberg)

Main Article

Table

Seropositivity of 1−4-year-old urban children for Zika virus and other flaviviruses, by province, Indonesia, October–November 2014*

Province Serologic status, % (no. positive samples/total samples)
Suspected Zika virus seropositive† Confirmed Zika virus seropositive‡ Flavivirus seropositive§
Aceh 0 (0/22) 0 (0/22) 0 (0/22)
North Sumatra 9.1 (2/22) 4.5 (1/22) 4.5 (1/22)
West Sumatra 18.2 (4/22) 13.6 (3/22) 4.5 (1/22)
Jambi 18.2 (4/22) 18.2 (4/22) 0 (0/22)
Lampung 8.7 (2/23) 8.7 (2/23) 0 (0/23)
Banten 4.4 (2/45) 4.4 (2/45) 0 (0/45)
DKI Jakarta 10.6 (7/66) 10.6 (7/66) 0 (0/66)
West Java 11.1 (17/153) 8.5 (13/153) 2.0 (3/153)
Central Java 20.5 (18/88) 18.2 (16/88) 2.3 (2/88)
East Java 11.7 (13/111) 9.0 (10/111) 2.7 (3/111)
Bali 0 (0/22) 0 (0/22) 0 (0/22)
East Kalimantan 4.5 (1/22) 4.5 (1/22) 0 (0/22)
South Sulawesi 0 (0/22) 0 (0/22) 0 (0/22)
Southeast Sulawesi
 13.6 (3/22)
 4.5 (1/22)
 9.1 (2/22)
All provinces 11.0 (73/662), 95% CI 5.34–13.32 9.1 (60/662), 95% CI 3.95–11.01 1.8 (12/662), 95% CI 0.23–3.35

*DENV, dengue virus; PRNT90, plaque reduction neutralization test with neutralization defined as >90% reduction in challenge virus PFUs.
†Serum samples that neutralized >90% of the challenge virus at a 1:10 dilution on initial Zika virus PRNT90 screening.
‡Serum samples that neutralized Zika virus only or had a PRNT90 titer >4-fold higher for Zika virus than for any DENV.
§Serum samples that neutralized Zika virus and DENV and had a PRNT90 titer for Zika virus that was <4-fold higher than that for any DENV.

Main Article

Page created: August 15, 2018
Page updated: August 15, 2018
Page reviewed: August 15, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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